Einstein Stem Cell Research Institute

爱因斯坦干细胞研究所

• 批准号: 7898006
• 负责人: ALLEN M. SPIEGEL
• 金额: $ 953.25万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-18 至 2014-03-18
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7898006
• 关键词: Area; Cell Separation; Cell Transplantation; Cellular biology; Commit; Core Facility; County; Development; Disease; Faculty; Funding; Genetic; Housing; Institutes; Laboratories; Laboratory Research; Medicine; Molecular Biology; New York; Occupations; Play; Price; Regenerative Medicine; Research; Research Institute; Research Personnel; Resources; Role; Source; Stem Cell Research; Stem cells; Strategic Planning; Unemployment; United States National Institutes of Health; Wing; base; cancer stem cell; college; developmental genetics; epigenomics; innovation; programs; research facility; stem cell biology; translational medicine

DESCRIPTION (provided by applicant): The Albert Einstein College of Medicine Strategic Research Plan established a Stem Cell Research Institute (SCRI) that will create cross-cutting opportunities in stem cell research and regenerative medicine. Currently, Einstein has a faculty base of 21 investigators involved in stem cell research who are located in various buildings across the campus. Given its key role in Einstein's Strategic Plan, the SCRI has been committed a full wing in the new $200 million Price Center for Genetic and Translational Medicine, plus resources for faculty recruitment and development of core facilities. The Price Center houses the new director of the Institute, as well as the Center for Epigenomics that plays a major role. This proposal aims to create space for 12 senior stem cell investigators, generating the expanded space by renovating and modernizing laboratories for an integrated network of stem cell research facilities. The SCRI is supported by external sources, including the NIH and the New York State Stem Cell Research program. We propose to organize the SCRI around four areas of research: 1) Stem Cell Biology, 2) Stem Cell Genetics, 3) Cancer Stem Cells, and 4) Translational Stem Cell Research. In order to synergize with existing stem cell researchers, we envision that the SCRI will expand basic and translational stem cell research by co-recruitment of faculty in the departments of Cell Biology, Genetics, and Developmental and Molecular Biology. Pursuant to the Strategic Plan, these 3 departments have contributed a total of 17,970 nsf of laboratory space to house new stem cell investigators to expand the scientific research base. The focus of this application is therefore to expand the new Stem Cell Research Institute to create new laboratories and to expand the related stem cell core facilities for cell sorting and cell transplantation. The C06 funds will create 85 jobs related to construction and 68 new research laboratory jobs. This is both economically critical for the 1.4 million people in the Bronx, the county within New York that has one of the highest unemployment rates, as well as creating a major driver of scientific innovation to create the cures for multiple diseases.)

描述（由申请人提供）：阿尔伯特·爱因斯坦医学院战略研究计划建立了干细胞研究所（SCRI），该研究所将为干细胞研究和再生医学创造交叉机会。目前，爱因斯坦拥有 21 名从事干细胞研究的研究人员，他们分布在校园的各个建筑中。鉴于其在爱因斯坦战略计划中的关键作用，SCRI 已投入耗资 2 亿美元新建的遗传与转化医学价格中心，并提供用于教师招聘和核心设施开发的资源。普莱斯中心是研究所的新任所长，以及发挥重要作用的表观基因组学中心。该提案旨在为 12 名高级干细胞研究人员创造空间，通过改造和现代化实验室来建立干细胞研究设施的综合网络，从而扩大空间。 SCRI 得到外部资源的支持，包括 NIH 和纽约州干细胞研究计划。我们建议围绕四个研究领域组织 SCRI：1) 干细胞生物学，2) 干细胞遗传学，3) 癌症干细胞，4) 转化干细胞研究。为了与现有的干细胞研究人员协同作用，我们预计 SCRI 将通过共同招聘细胞生物学、遗传学、发育和分子生物学系的教员来扩大基础和转化干细胞研究。根据战略计划，这三个部门共贡献了17,970 nsf的实验室空间，用于容纳新的干细胞研究人员，以扩大科学研究基地。因此，该申请的重点是扩建新的干细胞研究所以创建新的实验室，并扩大用于细胞分选和细胞移植的相关干细胞核心设施。 C06 资金将创造 85 个与建筑相关的工作岗位和 68 个新的研究实验室工作岗位。这对于布朗克斯区（纽约州失业率最高的县之一）的 140 万人来说，在经济上至关重要，同时也为科学创新创造了治疗多种疾病的方法的主要驱动力。）