Institute on Aging Clinical Translational Research Building

描述(由申请人提供)：佛罗里达州60岁或以上人口的比例是全国最大的(17.8%)，这一年龄段是人口增长最快的部分。在2000年的美国人口普查中，超过320万佛罗里达州人，即该州人口的22.2%，报告患有残疾。随着人口继续老龄化，老年美国人将全职或季节性地搬到我们州，佛罗里达州的残疾美国人数量将会上升。老年人有许多独特和复杂的医疗保健需求，因此，佛罗里达州的学术医疗中心面临着开发能够解决老年人特殊健康问题的研究计划和研究设施的重大挑战。为了应对日益增长的医疗保健需求和老龄化社区日益增长的人口，我们提议建造佛罗里达大学(UF)老年临床翻译研究大楼(IOA-CTRB)，该大楼占地39,500 GSF，将有助于开发旨在改善美国老年人健康、独立性和生活质量的新研究方法。虽然对综合设施的需求很大，但在密歇根大学校园和佛罗里达州，完全缺乏与拟议的IOA-CTRB类似的资源。IOA-CTRB将创造一个连贯的环境，促进对老龄化和残疾问题的全面研究。为了有效满足与老年人口相关的新出现的临床研究需求，并促进所有阶段的转化研究，我们提议建造39,500 GSF的IOA-CTRB，这是一座领先的能源与环境设计(LEED)白金大楼，将容纳以下新的共享资源：临床研究评估设施、生物标本处理和储存库、招募和保留核心、行为和生活方式改变干预设施、流行病学和老龄健康服务实验室、创意思维、会议和培训资源的办公中心，以及无障碍停车场。IOA-CTRB将在整个校园范围内发挥重大影响，刺激和维持UF和该地区关于老龄化的研究和研究事业发展。IOA-CTRB应用程序的主要优势包括强大的项目领导力、大量保留或创造的美国就业机会、出色的机构支持、IOA-CTRB提供的独特单点资源、创新的先进绿色/可持续设计和生活质量原则、非凡的资金支持以及悬而未决的IOA拨款记录、影响深远的研究事业发展计划、新的认知老龄化和记忆临床转化研究计划(CAM-CTRP)，以及最重要的NIH和CDC资助的中心拨款，例如在佛罗里达州独一无二的Pepper老年美国人独立中心(OAIC)、临床翻译科学研究所(CTSI)和佛罗里达州残疾人健康办公室(FOHD)。这些中心赠款代表着IOA的研究和研究事业发展的支柱，并支持目前和未来在老龄领域和IOA-CTRB领域的现有和未来资助赠款的实施和长期可持续性和成功。综上所述，所有这些资产最终将对美国老年人的健康、独立和生活质量产生积极影响。这项提案将为建设项目创造或保留总计283个就业机会，新设施将创造或保留93个就业机会。总的影响将是创造或保留376个美国就业机会。

DESCRIPTION (provided by applicant): The state of Florida has the largest proportion (17.8%) of persons age 60 years or older in the nation and this age group represents the fastest growing segment of the population. In the 2000 US Census, more than 3.2 million Floridians, or 22.2% of the state's population, reported having a disability. As the population continues to age and older Americans relocate full-time or seasonally to our state, the number of disabled Americans in Florida will rise. Older adults have a number of unique and complex health care needs, and as such, academic medical centers in the state of Florida face a significant challenge to develop research programs, and research facilities that can address the special health problems of older persons. In response to the growing health care needs and increasing population of the aging community, we propose to construct the University of Florida (UF) Institute on Aging Clinical Translational Research Building (IOA-CTRB) of 39,500 GSF, which will be instrumental for developing novel research approaches aimed at improving the health, independence and quality of life of older Americans. While the need for a comprehensive facility is substantial, a comparable resource to the proposed IOA- CTRB is completely lacking on the UF campus and in Florida. The IOA-CTRB will create a cohesive environment that will promote a holistic approach to research on aging and disability. To effectively address the emerging clinical research needs regarding the older populations and to promote all stages of translational research we propose to construct the IOA-CTRB of 39,500 GSF, a Leadership in Energy and Environmental Desing (LEED) platinum building, which will host the following new shared resources: clinical research assessment facility, biological specimens processing and repository, recruitment and retention core, behavioral and lifestyle modification intervention facility, laboratory of epidemiology and health services of aging, office hub for creative thinking, conference and training resources, and accessible parking. The IOA-CTRB will exert a major campus-wide impact in stimulating and sustaining research and research career development on aging at UF and in the region. Major strengths of this IOA-CTRB application are strong project leadership, sizeable number of American jobs retained or created, remarkable institutional support, unique single point of entry resources offered by the IOA-CTRB, innovative advanced green/sustainable design and quality of life principles, exceptional funded and pending IOA grant record, far reaching research career development programs, new Cognitive Aging and Memory Clinical Translational Research Program (CAM-CTRP), and most importantly NIH and CDC funded center grants, such as the Pepper Older Americans Independence Center (OAIC), the Clinical Translational Sciences Institute (CTSI) and the Florida Office on Disability Health (FOHD) that are unique in Florida. These center grants represent the research and research career development backbone for the IOA and support the implementation and long- term sustainability and success of the current and future funded grants in the area of aging and of the IOA- CTRB. Taken together, all these assets will ultimately positively impact on the health, independence and quality of life of older Americans. This proposal will create or retain a total of 283 jobs for the construction project and 93 jobs will be created or retained in the new facility. The total impact will be on the creation or retention of 376 American jobs.