Pediatric Graft-vs-Host Disease

儿童移植物抗宿主病

• 批准号: 7064436
• 负责人: alan s wayne
• 金额: --
• 依托单位: DIVISION OF BASIC SCIENCES - NCI
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7064436
• 关键词: bone marrow transplantation; children; disease /disorder etiology; graft versus host disease

The primary goal is to advance understanding of the pathobiology and natural history of and to develop new strategies to prevent and treat graft-versus-host disease in pediatric patients. This is a collaborative project led by the NCI Experimental Transplantation Immunology Branch in collaboration with multiple NIH Intramural Investigators. The following projects/efforts are currentlyunderway or in preparation: 1) Natural History Trial of GVHD; 2) Extracorporeal Photophersis; 3) National Working Groups to Develop Diagnostic Standards and Supportive Care Guidelines; 4) Novel Therapeutics for GVHD

主要目标是促进对儿科患者移植物抗宿主病的病理生物学和自然史的理解，并制定预防和治疗移植物抗宿主病的新策略。这是一个由NCI实验移植免疫学分支与多个NIH校内研究人员合作领导的合作项目。目前正在进行或筹备的项目/工作如下：1)GVHD自然历史试验；2)体外光合作用；3)制定诊断标准和支持性护理指南的国家工作组；4) GVHD的新疗法