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Pediatric Graft-vs-Host Disease

Pediatric Graft-vs-Host Disease
儿童移植物抗宿主病
批准号：
7592789
负责人：
alan s wayne
金额：
$29.64万
依托单位：
DIVISION OF BASIC SCIENCES - NCI
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/7592789
关键词：
AdolescentAdultAllogenicChildChildhoodChronicDataDevelopmentDiagnosticDiseaseDisease-Free SurvivalGoalsGrowthGuidelinesHematopoietic Stem Cell TransplantationLifeMorbidity - disease rateNatural HistoryOrganPatientsPediatricsPopulationRangeRecurrenceResearchResearch PersonnelStandards of Weights and MeasuresStem cell transplantSupportive careTransplantationTransplantation ImmunologyUnited States National Institutes of HealthWorkbench to bedsidechronic graft versus host diseasegraft vs host diseasemortalitynovel therapeuticspreventresponse

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中文摘要
翻译
主要目标是促进对儿科患者移植物抗宿主病的病理生物学和自然史的理解，并制定预防和治疗移植物抗宿主病的新策略。这是一个与NCI实验移植免疫学分支和多个NIH校内研究者合作的项目。目前正在开展的项目/工作有：1)GVHD自然历史研究；2)慢性GVHD患儿体外光合作用的临床转化研究；3)制定诊断标准和支持性护理指南的国家工作组；4) GVHD的新疗法
英文摘要
The primary goal is to advance understanding of the pathobiology and natural history of and to develop new strategies to prevent and treat graft-versus-host disease in pediatric patients. This is a collaborative project with the NCI Experimental Transplantation Immunology Branch and multiple NIH Intramural Investigators. The following projects/efforts are currently underway: 1) Natural History Study of GVHD; 2) Bench-to-Bedside Translational Development of Extracorporeal Photophersis for childrenn with chronic GVHD; 3) National Working Groups to Develop Diagnostic Standards and Supportive Care Guidelines; 4) Novel Therapeutics for GVHD
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Pediatric Oncology Branch Clinical Care and Education
Experimental Therapeutics of Pediatric Hematopoietic Malignancies
Pediatric Oncology Branch Clinical Care and Education
Pediatric Graft-vs-Host Disease
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