Pediatric Graft-vs-Host Disease

儿童移植物抗宿主病

• 批准号: 8158325
• 负责人: alan s wayne
• 金额: $ 9.86万
• 依托单位: DIVISION OF BASIC SCIENCES - NCI
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8158325
• 关键词: Childhood; graft vs host disease

The primary goal is to advance understanding of the pathobiology and natural history of and to develop new strategies to prevent and treat graft-versus-host disease in pediatric patients. This is a collaborative project with the NCI Experimental Transplantation Immunology Branch and multiple NIH Intramural Investigators. The following projects/efforts are currently underway: 1) Natural History Study of GVHD; 2) Bench-to-Bedside Translational Development of Extracorporeal Photophersis for childrenn with chronic GVHD; 3) National Working Groups to Develop Diagnostic Standards and Supportive Care Guidelines; 4) Novel Therapeutics for GVHD

主要目标是促进对移植物抗宿主病的病理生物学和自然病史的了解，并开发新的策略来预防和治疗儿科患者的移植物抗宿主病。这是一个与NCI实验移植免疫学分会和多名NIH内部调查人员合作的项目。目前正在进行以下项目/努力：1)GVHD的自然史研究；2)慢性GVHD儿童体外光疗的床边翻译开发；3)制定诊断标准和支持性护理指南的国家工作组；4)GVHD的新治疗方法

项目成果

Hematopoietic stem cell transplantation for leukemia.

• DOI: 10.1016/j.pcl.2009.11.005
• 发表时间: 2010-02
• 期刊: PEDIATRIC CLINICS OF NORTH AMERICA
• 影响因子: 2.6
• 作者: Wayne, Alan S.;Baird, Kristin;Egeler, R. Maarten
• 通讯作者: Egeler, R. Maarten

Application of immunotherapy in pediatric leukemia.

免疫治疗在小儿白血病中的应用。

• DOI: 10.1007/s11899-009-0022-5
• 发表时间: 2009
• 期刊: Current hematologic malignancy reports
• 影响因子: 2.9
• 作者: Wayne,AlanS