Histotechnology Core

申请的组织技术核心为该计划中的所有调查人员提供访问权限-项目赠款 啮齿动物组织的组织技术服务和诊断服务。目前可用 这种类型的支持服务正在超负荷工作。只有两名组织技术员和几名 本科生助教。他们目前为18名教职员工提供服务，去年 制作了8万多张各种类型的幻灯片。一位经验丰富的组织技术专家要求 将致力于该计划成员的项目-项目赠款，不仅提供常规的，而且提供各种 固定和冷冻组织样本的专门组织技术方法，包括酶组织化学， 免疫组织化学和放射自显影。预计这名个人还将接受 原位杂交，这是这些项目目前无法使用的一种技术。这项技术将是必不可少的 项目赠款中的几个项目。组织病理学解释将由CORE提供 这项资助的成员所需要的董事。

The Histotechnology Core requested provides access to all investigators in this program-project grant to histotechnology services and diagnostic services for tissues obtained from rodents. Currently available support services of this type are working at overload capacity .with only two histotechnologists and several undergraduate student assistants. They are presently servicing 18 faculty members, which in the last year produced more than 80,000 slides of a variety of types. The single experienced histotechnologist requested will work on projects for members of this program-project grant, providing not only routine but a variety of specialized histotechnology methods on both fixed and frozen tissue samples, including enzyme histochemistry, immunohistochemistry, and autoradiography. It is anticipated that this individual will also be trained in in situ hybridization, a technique presently not available to these projects. This technology will be essential to several projects in the program-project grant. Histopathologic interpretation will be provided by the Core director as needed by members of this grant.