Experimental Pathology

实验病理学

• 批准号: 7491885
• 负责人: Henry C Pitot, Jr.
• 金额: $ 18万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-23 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7491885
• 关键词: Animal Model; Autoradiography; Biological Assay; Caliber; Consultations; Cultured Cells; Detection; Development; Diagnostic Services; Experimental Designs; Experimental Pathology; Freezing; Histologic; Human; Malignant Neoplasms; Methods; Mission; Molecular; Paraffin Embedding; Pathologist; Preparation; Procedures; Range; Research; Research Personnel; Sampling; Services; Specimen; Staining method; Stains; Techniques; Testing; Tissues; in vivo; interest; neoplastic; programs

The Experimental Pathology Shared Service provides UWCCC investigators with histologic preparations of the highest caliber workmanship using a variety of procedures. Techniques range from classical histologic staining methods to cutting edge molecular histopathologic assays, such as immunohistochemical detection of molecules of interest. The facility additionally offers consultation services, by which UWCCC investigators can obtain the assistance of a.Pathologist in the examination and interpretation of their samples. The Pathologists are also available to discuss experimental design with interested investigators. Serial sections , of both frozen and paraffin-embedded material are routinely carried out, as well as autoradiography of tissue sections and cell cultures with appropriate stains. Drs. Ruth Sullivan and Henry C. Pitot offer consultation to investigators whenever the need arises. The ability of UWCCC investigators to fully characterize animal models of human cancer and to test hypotheses regarding mechanisms of neoplastic development in vivo depends on both the technical and diagnostic services of the Experimental Pathology Facility.

实验病理学共享服务为UWCCC研究人员提供以下组织学准备： 采用多种工艺的最高水准的工艺。技术范围从经典的组织学 染色方法，以尖端的分子组织病理学检测，如免疫组织化学检测 我们感兴趣的分子该设施还提供咨询服务，UWCCC调查人员 在检验和解释其样本时，可获得病理学家的协助。的 病理学家也可以与感兴趣的研究人员讨论实验设计。连续切片， 常规进行冷冻和石蜡包埋材料的放射自显影以及组织的放射自显影 切片和细胞培养物用适当的染色。鲁思·沙利文和亨利·C.皮托提供咨询， 调查人员，只要有需要。UWCCC研究人员充分描述动物特征的能力 人类癌症模型，并测试关于体内肿瘤发展机制的假设 这取决于实验病理学设施的技术和诊断服务。