Experimental Pathology

实验病理学

• 批准号: 8250410
• 负责人: Henry C Pitot, Jr.
• 金额: $ 15.03万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8250410
• 关键词: Animal Model; Autoradiography; Biological Assay; Caliber; Cell Culture Techniques; Comprehensive Cancer Center; Consultations; Detection; Development; Diagnostic Services; Experimental Designs; Experimental Pathology; Freezing; Histologic; Human; Malignant Neoplasms; Mission; Molecular; Paraffin Embedding; Pathologist; Preparation; Procedures; Research; Research Personnel; Sampling; Services; Specimen; Staining method; Stains; Techniques; Testing; Tissues; in vivo; interest; neoplastic; programs

The Experimental Pathology Shared Service provides UWCCC investigators with histologic preparations of the highest caliber workmanship using a variety of procedures. Techniques range from classical histologic staining methods to cutting edge molecular histopathologic assays, such as immunohistochemical detection of molecules of interest. The facility additionally offers consultation services, by which UWCCC investigators can obtain the assistance of a.Pathologist in the examination and interpretation of their samples. The Pathologists are also available to discuss experimental design with interested investigators. Serial sections , of both frozen and paraffin-embedded material are routinely carried out, as well as autoradiography of tissue sections and cell cultures with appropriate stains. Drs. Ruth Sullivan and Henry C. Pitot offer consultation to investigators whenever the need arises. The ability of UWCCC investigators to fully characterize animal models of human cancer and to test hypotheses regarding mechanisms of neoplastic development in vivo depends on both the technical and diagnostic services of the Experimental Pathology Facility.

实验病理学共享服务为UWCCC研究人员提供 最高口径的做工采用了各种程序。技术范围从经典组织学到 免疫组织化学检测等前沿分子组织病理学检测的染色方法 感兴趣的分子。该设施还提供咨询服务，通过该服务，UWCCC调查人员 可在检查和解释其样本时获得病理学家的协助。这个 病理学家也可以与感兴趣的研究人员讨论实验设计。连载部分， 常规进行冷冻和石蜡包埋材料的检查，以及组织的放射自显影 切片和细胞培养，用适当的染色。露丝·沙利文博士和亨利·C·皮特博士为 只要有需要，调查人员就会出动。UWCCC调查人员充分描述动物特征的能力 建立人类癌症模型并检验关于体内肿瘤发展机制的假说 取决于实验病理学设施的技术和诊断服务。