Predoctoral Training Program in Biotechnology

描述(由申请人提供)：项目概要：本申请请求继续支持1990年首次资助的生物技术博士前培训计划。二十八名教师分别来自八个系及四个学院：化学、生物科学(文理学院)；生物化学、微生物学、药理学(医学院)；土木与环境工程、化学及生化工程(工程学院)；药物及天然产品化学(药学院)。这个多元化的教职员工为受训者提供学科背景，使他们能够在各自的系获得博士学位。以下要求的活动提供了适合生物技术职业的跨学科背景：a)生物技术三个核心领域(生物催化、生物反应器和生物分离、分子生物学和遗传学)中每一个领域至少有一门课程；b)参加跨学科研讨会“生物催化前景”；c)参加生物催化研讨会方案；d)参加题为“负责任的研究行为”的课程；e)在工业或政府实验室实习；f)在年度生物催化和生物处理会议上展示研究成果。要求为9名博士前实习生提供支持。学员在研究生院二年级时进入该项目，并可续签最多三年的支持。培训计划由计划主任(Daniel M.Quinn)管理，生物催化和生物处理中心(CBB)的工作人员协助，并听取协调委员会的建议。协调委员会也是CBB的执行委员会，从而确保培训方案和国家资助的中心之间的密切协调。培训方案的一个重点是招募和培训各种不同的受训人员。这一重点不仅满足了各国的需要，还为受训人员提供了更具包容性的教育体验。 相关性：参与的学院实验室为学员提供了广泛的生物医学科学研究机会。其中包括对环境友好的化学转化生物催化过程的研究，新抗生素和阿尔茨海默病药物的开发，生物传感器的开发，以及基因传递的新方法。

DESCRIPTION (provided by applicant): Project Summary: This application requests continued support for a Predoctoral Training Program in Biotechnology that was first funded in 1990. Twenty eight participating faculty are drawn from eight departments and four colleges: Chemistry, Biological Sciences (College of Liberal Arts & Sciences); Biochemistry, Microbiology, Pharmacology (College of Medicine); Civil & Environmental Engineering, Chemical & Biochemical Engineering (College of Engineering); Medicinal and Natural Products Chemistry (College of Pharmacy). This diverse faculty provides trainees with disciplinary backgrounds that lead to the Ph.D. degree in their respective departments. The following required activities provide the interdisciplinary background appropriate for biotechnology-oriented careers: a) at least one course in each of the three core areas of biotechnology (Biocatalysis, Bioreactors & Bioseparations, Molecular Biology & Genetics); b) participation in the interdisciplinary seminar "Perspectives in Biocatalysis"; c) participation in the Biocatalysis Seminar Program; d) take a course entitled "Responsible Conduct of Research"; e) serve an internship in an industrial or government laboratory; f) present research in the annual Biocatalysis and Bioprocessing Conference. Support for 9 predoctoral trainees is requested. Trainees enter the program in their second year of graduate school, and may be renewed for up to three years of support. The Training Program is administered by the Program Director (Daniel M. Quinn), with staff assistance from the Center for Biocatalysis and Bioprocessing (CBB) and the advice of the Coordinating Committee. The Coordinating Committee also serves as the Executive Committee of the CBB, thereby insuring close coordination between the Training Program and the state-funded Center. An emphasis of the Training Program is the recruitment and training of a diverse cohort of trainees. This emphasis not only addresses national needs but also provides a more inclusive educational experience for the trainees. Relevance: Participating faculty laboratories provide trainees with a wide range of research opportunities in the biomedical sciences. Among these are investigations of environmentally friendly biocatalytic processes for chemical transformations, development of new antibiotics and Alzheimer's disease agents, biosensor development, and new approaches to gene delivery.