Predoctoral Training Program in Biotechnology

描述（由申请人提供）：项目概述：本申请要求继续支持生物技术博士前培训计划，该计划于1990年首次资助。28名参与的教师来自8个系和4个学院：化学、生物科学（文理学院）；生物化学、微生物学、药理学（医学院）；土木与环境工程、化学与生化工程（工学院）；药物与天然产物化学（药学院）。这种多元化的师资队伍为学员提供了各自院系的学科背景，使他们能够获得博士学位。以下要求的活动提供适合生物技术导向职业的跨学科背景：a)在生物技术的三个核心领域（生物催化，生物反应器与生物分离，分子生物学与遗传学）中至少一门课程；b)参加跨学科研讨会“生物催化展望”；c)参加生物催化研讨会计划；d)参加一门名为“负责任的研究行为”的课程；E)在工业或政府实验室实习；f)在年度生物催化和生物加工会议上展示研究成果。请支助9名博士预科学员。学员在研究生院的第二年进入该项目，并可能续签长达三年的支持。培训计划由项目主任（Daniel M. Quinn）管理，生物催化和生物处理中心（CBB）的工作人员提供协助，并听取协调委员会的建议。协调委员会同时担任CBB的执行委员会，从而确保培训计划与国家资助的中心之间的密切协调。培训计划的一个重点是招聘和培训不同的学员群体。这种强调不仅满足了国家的需要，而且为受训者提供了更具包容性的教育经验。

DESCRIPTION (provided by applicant): Project Summary: This application requests continued support for a Predoctoral Training Program in Biotechnology that was first funded in 1990. Twenty eight participating faculty are drawn from eight departments and four colleges: Chemistry, Biological Sciences (College of Liberal Arts & Sciences); Biochemistry, Microbiology, Pharmacology (College of Medicine); Civil & Environmental Engineering, Chemical & Biochemical Engineering (College of Engineering); Medicinal and Natural Products Chemistry (College of Pharmacy). This diverse faculty provides trainees with disciplinary backgrounds that lead to the Ph.D. degree in their respective departments. The following required activities provide the interdisciplinary background appropriate for biotechnology-oriented careers: a) at least one course in each of the three core areas of biotechnology (Biocatalysis, Bioreactors & Bioseparations, Molecular Biology & Genetics); b) participation in the interdisciplinary seminar "Perspectives in Biocatalysis"; c) participation in the Biocatalysis Seminar Program; d) take a course entitled "Responsible Conduct of Research"; e) serve an internship in an industrial or government laboratory; f) present research in the annual Biocatalysis and Bioprocessing Conference. Support for 9 predoctoral trainees is requested. Trainees enter the program in their second year of graduate school, and may be renewed for up to three years of support. The Training Program is administered by the Program Director (Daniel M. Quinn), with staff assistance from the Center for Biocatalysis and Bioprocessing (CBB) and the advice of the Coordinating Committee. The Coordinating Committee also serves as the Executive Committee of the CBB, thereby insuring close coordination between the Training Program and the state-funded Center. An emphasis of the Training Program is the recruitment and training of a diverse cohort of trainees. This emphasis not only addresses national needs but also provides a more inclusive educational experience for the trainees. Relevance: Participating faculty laboratories provide trainees with a wide range of research opportunities in the biomedical sciences. Among these are investigations of environmentally friendly biocatalytic processes for chemical transformations, development of new antibiotics and Alzheimer's disease agents, biosensor development, and new approaches to gene delivery.