Function and physiological role of inhibitory circuits in the amygdala

杏仁核抑制回路的功能和生理作用

• 批准号: nhmrc : 1062183
• 负责人: Prof Joseph Lynch
• 金额: $ 49.44万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/function-physiological-role-circuits-amygdala/454964
• 关键词: Function; physiological; role; inhibitory; circuits

The amygdala is part of the brain that assigns emotional content to our sensory world and dysfunction of the amygdala is responsible for many anxiety-related disorders. Many anxiolytics, like valium, act on receptors in the amygdala. In this project we will study circuits in the amygdala that are modulated by anxiolytics. These studies will provide essential information in the understanding of anxiety disorders and help in developing drugs to treat these disorders.

杏仁核是大脑的一部分，负责将情感内容分配给我们的感官世界，杏仁核的功能障碍是许多焦虑相关疾病的原因。许多抗焦虑药，如安定，作用于杏仁核中的受体。在这个项目中，我们将研究由抗焦虑药调制的杏仁核回路。这些研究将为理解焦虑症提供重要信息，并有助于开发治疗这些疾病的药物。