The molecular basis of ionic selectivity in nicotinic-type ion channel receptors

烟碱型离子通道受体离子选择性的分子基础

• 批准号: DP130101702
• 负责人: Prof Joseph Lynch
• 金额: $ 24.87万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP130101702
• 关键词: molecular; basis; ionic; selectivity; nicotinic

The ability of cell membranes to transport sodium, potassium and chloride selectively is important for many physiological processes. By elucidating the mechanisms by which membrane ion channels flux chloride ions, selectively this project will have wide-ranging ramifications from understanding physiological processes to nanofluidic device design.

细胞膜选择性运输钠、钾和氯的能力对于许多生理过程是重要的。通过阐明膜离子通道通量氯离子的机制，选择性地，该项目将有广泛的分支，从了解生理过程到纳米流体设备设计。