The Effects of Human Epilepsy Mutations on Synaptic GABA-A Receptors Studied by Localization-based Superresolution Microscopy
The Effects of Human Epilepsy Mutations on Synaptic GABA-A Receptors Studied by Localization-based Superresolution Microscopy
批准号:
nhmrc : 1147600
负责人:
Prof Joseph Lynch
金额:
$34.95万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2020-12-31
中文摘要
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英文摘要
The genetic epilepsies are debilitating neurological disorders that are frequently associated with mutations in genes encoding neurotransmitter-gated receptors in the brain. The goal of this project is to understand mechanisms that cause changes in neuronal communication and lead to epilepsy on a single receptor level. This will lead to an improved understanding of the mechanisms of epileptogenesis and new insights into ways of treating different epilepsies.
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