Furin: Carving-up vital substrates for bone remodelling and homeostasis
Furin: Carving-up vital substrates for bone remodelling and homeostasis
批准号:
nhmrc : GNT1107828
负责人:
A/Pr Nathan Pavlos
金额:
$81.6万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Osteoporosis, or porous bone, is a disease characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility and an increased susceptibility to fractures. It is caused by an imbalance between the cells that are constantly reabsorbing and reforming bone. The proposed project will address furin as a novel regulator of bone remodelling.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
The Role of 'Orphan' Transporters in Bone Homeostasis and Disease
-
批准号:nhmrc : GNT1143921
-
项目类别:Project Grants
-
资助金额:$67.57万
-
财政年份:2018
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
The Role of 'Orphan' Transporters in Bone Homeostasis and Disease
-
批准号:nhmrc : 1143921
-
项目类别:Project Grants
-
资助金额:$45.68万
-
财政年份:2018
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Gene mining for novel molecular determinants of the skeleton
-
批准号:nhmrc : GNT1127156
-
项目类别:Project Grants
-
资助金额:$63.34万
-
财政年份:2017
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Gene mining for novel molecular determinants of the skeleton
-
批准号:nhmrc : 1127156
-
项目类别:Project Grants
-
资助金额:$43.23万
-
财政年份:2017
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Furin: Carving-up vital substrates for bone remodelling and homeostasis
-
批准号:nhmrc : 1107828
-
项目类别:Project Grants
-
资助金额:$56.14万
-
财政年份:2016
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
The role of Sorting Nexin 27 in cargo-trafficking during skeletal homeostasis
-
批准号:nhmrc : GNT1078280
-
项目类别:Project Grants
-
资助金额:$40.26万
-
财政年份:2015
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
The role of Sorting Nexin 27 in cargo-trafficking during skeletal homeostasis
-
批准号:nhmrc : 1078280
-
项目类别:Project Grants
-
资助金额:$41.56万
-
财政年份:2015
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Molecular Characterization of V-ATPase V0 Domain Subunits e1 and e2 in Osteoclast
-
批准号:nhmrc : 1049884
-
项目类别:Project Grants
-
资助金额:$37.27万
-
财政年份:2013
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Myo1b bridges the actin-membrane interface during osteoclastic bone resorption
-
批准号:nhmrc : 1029292
-
项目类别:Project Grants
-
资助金额:$28.63万
-
财政年份:2012
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Paget's disease of bone associated Sequestosome 1/p62 mutations in autophagy-mediated processes and bone resorption
-
批准号:nhmrc : 1027932
-
项目类别:Project Grants
-
资助金额:$31.67万
-
财政年份:2012
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Molecular Mechanisms and Therapeutic Effects of Novel Parthenolide Analogs on Osteolysis
-
批准号:nhmrc : 1010420
-
项目类别:NHMRC Project Grants
-
资助金额:$37.53万
-
财政年份:2011
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Roquin plays a critical role in bone homeostasis
-
批准号:nhmrc : 1010256
-
项目类别:NHMRC Project Grants
-
资助金额:$31.97万
-
财政年份:2011
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Interaction of Rab3D and Tctex-1 is required for bone resorption through the regulation of post-TGN vesicle trafficking
-
批准号:nhmrc : 458765
-
项目类别:NHMRC Project Grants
-
资助金额:$26.11万
-
财政年份:2007
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
The role of Tctex-1 in Rab3D-mediated osteoclastic bone resorption.
-
批准号:nhmrc : 463911
-
项目类别:Early Career Fellowships
-
资助金额:$21.2万
-
财政年份:2007
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
海外基金