The role of Sorting Nexin 27 in cargo-trafficking during skeletal homeostasis
The role of Sorting Nexin 27 in cargo-trafficking during skeletal homeostasis
批准号:
nhmrc : 1078280
负责人:
A/Pr Nathan Pavlos
金额:
$41.56万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2018-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Skeletal diseases encompass a devastating set of disorders ranging from heritable skeletal dysplasia’s such as dwarfism through to degenerate diseases like osteoporosis. This research project aims to determine the role of a protein called Sorting Nexin 27 (SNX27), normally involved in the transport of intracellular cargo (e.g. growth factor receptors), in the maintenance of the skeleton and its potential contribution to the pathogenesis of skeletal disorders.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
The Role of 'Orphan' Transporters in Bone Homeostasis and Disease
-
批准号:nhmrc : GNT1143921
-
项目类别:Project Grants
-
资助金额:$67.57万
-
财政年份:2018
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
The Role of 'Orphan' Transporters in Bone Homeostasis and Disease
-
批准号:nhmrc : 1143921
-
项目类别:Project Grants
-
资助金额:$45.68万
-
财政年份:2018
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Gene mining for novel molecular determinants of the skeleton
-
批准号:nhmrc : GNT1127156
-
项目类别:Project Grants
-
资助金额:$63.34万
-
财政年份:2017
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Gene mining for novel molecular determinants of the skeleton
-
批准号:nhmrc : 1127156
-
项目类别:Project Grants
-
资助金额:$43.23万
-
财政年份:2017
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Furin: Carving-up vital substrates for bone remodelling and homeostasis
-
批准号:nhmrc : GNT1107828
-
项目类别:Project Grants
-
资助金额:$81.6万
-
财政年份:2016
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Furin: Carving-up vital substrates for bone remodelling and homeostasis
-
批准号:nhmrc : 1107828
-
项目类别:Project Grants
-
资助金额:$56.14万
-
财政年份:2016
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
The role of Sorting Nexin 27 in cargo-trafficking during skeletal homeostasis
-
批准号:nhmrc : GNT1078280
-
项目类别:Project Grants
-
资助金额:$40.26万
-
财政年份:2015
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Molecular Characterization of V-ATPase V0 Domain Subunits e1 and e2 in Osteoclast
-
批准号:nhmrc : 1049884
-
项目类别:Project Grants
-
资助金额:$37.27万
-
财政年份:2013
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Myo1b bridges the actin-membrane interface during osteoclastic bone resorption
-
批准号:nhmrc : 1029292
-
项目类别:Project Grants
-
资助金额:$28.63万
-
财政年份:2012
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Paget's disease of bone associated Sequestosome 1/p62 mutations in autophagy-mediated processes and bone resorption
-
批准号:nhmrc : 1027932
-
项目类别:Project Grants
-
资助金额:$31.67万
-
财政年份:2012
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Molecular Mechanisms and Therapeutic Effects of Novel Parthenolide Analogs on Osteolysis
-
批准号:nhmrc : 1010420
-
项目类别:NHMRC Project Grants
-
资助金额:$37.53万
-
财政年份:2011
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Roquin plays a critical role in bone homeostasis
-
批准号:nhmrc : 1010256
-
项目类别:NHMRC Project Grants
-
资助金额:$31.97万
-
财政年份:2011
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
Interaction of Rab3D and Tctex-1 is required for bone resorption through the regulation of post-TGN vesicle trafficking
-
批准号:nhmrc : 458765
-
项目类别:NHMRC Project Grants
-
资助金额:$26.11万
-
财政年份:2007
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
The role of Tctex-1 in Rab3D-mediated osteoclastic bone resorption.
-
批准号:nhmrc : 463911
-
项目类别:Early Career Fellowships
-
资助金额:$21.2万
-
财政年份:2007
-
负责人:A/Pr Nathan Pavlos
-
依托单位:
国内基金
海外基金
Sorting Nexin 9 (SNX9)在听毛细胞表皮板中的功能研究
-
批准号:31371355
-
项目类别:面上项目
-
资助金额:70.0万元
-
批准年份:2013
-
负责人:徐志刚
-
依托单位:
Sorting nexin 16 蛋白的三维晶体结构研究
-
批准号:30870496
-
项目类别:面上项目
-
资助金额:32.0万元
-
批准年份:2008
-
负责人:刘劲松
-
依托单位: