Molecular Characterization of V-ATPase V0 Domain Subunits e1 and e2 in Osteoclast
Molecular Characterization of V-ATPase V0 Domain Subunits e1 and e2 in Osteoclast
批准号:
nhmrc : 1049884
负责人:
A/Pr Nathan Pavlos
金额:
$37.27万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2015-12-31
中文摘要
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英文摘要
Osteoporotic fractures in the elderly are often linked to increased mortality rates. Excess bone resorption is a major contributor to the onset of the disease. The proposed project focuses on the investigation of the molecular mechanisms of acid secretion that is required for the bone degradation in body. The project will examine the role of the proton pump in bone resorption and seek potential targets for the treatment of osteoporosis.
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财政年份:2016
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依托单位:
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依托单位:
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依托单位:
Paget's disease of bone associated Sequestosome 1/p62 mutations in autophagy-mediated processes and bone resorption
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依托单位:
Molecular Mechanisms and Therapeutic Effects of Novel Parthenolide Analogs on Osteolysis
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依托单位:
Roquin plays a critical role in bone homeostasis
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资助金额:$31.97万
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依托单位:
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财政年份:2007
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依托单位:
The role of Tctex-1 in Rab3D-mediated osteoclastic bone resorption.
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依托单位:
海外基金