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Molecular Characterization of V-ATPase V0 Domain Subunits e1 and e2 in Osteoclast

Molecular Characterization of V-ATPase V0 Domain Subunits e1 and e2 in Osteoclast
破骨细胞中 V-ATPase V0 结构域亚基 e1 和 e2 的分子表征
批准号:
nhmrc : 1049884
负责人:
A/Pr Nathan Pavlos
金额:
$37.27万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2015-12-31

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中文摘要
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英文摘要
Osteoporotic fractures in the elderly are often linked to increased mortality rates. Excess bone resorption is a major contributor to the onset of the disease. The proposed project focuses on the investigation of the molecular mechanisms of acid secretion that is required for the bone degradation in body. The project will examine the role of the proton pump in bone resorption and seek potential targets for the treatment of osteoporosis.
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The Role of 'Orphan' Transporters in Bone Homeostasis and Disease
  • 批准号:
    nhmrc : GNT1143921
  • 项目类别:
    Project Grants
  • 资助金额:
    $67.57万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Nathan Pavlos
  • 依托单位:
The Role of 'Orphan' Transporters in Bone Homeostasis and Disease
  • 批准号:
    nhmrc : 1143921
  • 项目类别:
    Project Grants
  • 资助金额:
    $45.68万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Nathan Pavlos
  • 依托单位:
Gene mining for novel molecular determinants of the skeleton
  • 批准号:
    nhmrc : GNT1127156
  • 项目类别:
    Project Grants
  • 资助金额:
    $63.34万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Nathan Pavlos
  • 依托单位:
Gene mining for novel molecular determinants of the skeleton
  • 批准号:
    nhmrc : 1127156
  • 项目类别:
    Project Grants
  • 资助金额:
    $43.23万
  • 财政年份:
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  • 负责人:
    A/Pr Nathan Pavlos
  • 依托单位:
海外基金