Howard/Hopkins Cancer Center Partnership

霍华德大学癌症中心(HUCC)和约翰霍普金斯综合癌症中心(JHCCC)、马里兰州和哥伦比亚特区所服务的地区，50多年来一直是美国癌症死亡率最高的地区之一。这些地区的少数民族居民受到癌症的影响不成比例，癌症已成为马里兰州巴尔的摩和华盛顿特区非裔美国人发病率和死亡率的主要原因。为了解决这一问题，HUCC和JHCCC已开始合作，以增加与癌症有关的筛查诊断、预防、治疗和支持性护理方面的生产性研究，特别关注非裔美国人的癌症。HUCC/JHCCC伙伴关系最初是由每个机构的教师参与的一系列合作努力，这些教师被组织成针对高优先领域的小组，自1999年9月以来一直得到国家癌症研究所(NCI)对JHCCC核心补助金的补充资金的支持。到目前为止，在HUCC/JHCCC伙伴关系的规划阶段取得的成功，以及在前列腺癌、胃肠癌和乳腺癌等几个领域取得的合作研究进展，促使提交了这笔赠款，以期获得资金，进一步加强伙伴关系活动。这项赠款提案的主要目的是继续发展HUCC和JHCCC之间的可持续伙伴关系，以加强两个机构的研究、培训、教育和外联任务。为了实现这一目标，HUCC/JHCCC伙伴关系将致力于在HUCC建立针对非裔美国人癌症的研究人员和科学计划，加强JHCCC涉及非裔美国人的基于人群的癌症研究，增加HUCC非裔美国职业研究人员的研究培训和职业发展的机会，并改进JHCCC侧重于非裔美国人职业发病率和死亡率的教育和推广计划。该提案寻求对HUCC的3个研究项目、2个试点研究项目4、1个试点教育项目和核心基础设施的支持，以及为进一步规划和发展HUCC/JHCCC伙伴关系提供的额外资金。在为HUCC/JHCCC伙伴关系请求的5年支持期间，随着这些初步研究和教育活动的进展，竞争独立资金的新项目、计划和优先发展的资源将被确定和支持。

The regions served by the Howard University Cancer Center (HUCC) and Johns Hopkins Comprehensive Cancer Center (JHCCC), Maryland and the District of Columbia, have had among the highest cancer death rates in the United States for more than fifty years. Minority residents of these regions have been disproportionately affected by cancer, and cancer has become a leading cause of morbidity and mortality for African-Americans in both Baltimore, Maryland, and Washington, D.C. To address this problem, HUCC and JHCCC have embarked on a partnership to increase productive research in screening diagnosis, prevention, treatment, and supportive care as it relates to cancer, with a special focus on cancer in African-Americans. The HUCC/JHCCC partnership, which began as a series of collaborative efforts involving faculty from each institution organized into groups targeting high priority areas, has been supported since September of 1999 by supplemental funds for the JHCCC core grant from the National Cancer Institute (NCI). The success realized thus far during the planning phases of the HUCC/JHCCC partnership, with c9ollaborative research progress in several areas, including prostate cancer, gastrointestinal cancer, and breast cancer, has prompted the submission of this grant in an attempt to secure funds to further augment partnership activities. The major aim of this grant proposal is to continue the development of a sustainable partnership between HUCC and JHCCC that enhances the research, training, education, and outreach missions of both institutions. To accomplish this goal, the HUCC/JHCCC partnership will work to build the research faculty and scientific programs at HUCC directed at cancer in African-Americans, to enhance population-based cancer studies at JHCCC involving African-Americans, to increase opportunities for research training and career development of African-American career researchers at HUCC, and to improve education and outreach programs at JHCCC focused on career morbidity and mortality among African- Americans. The proposal seeks support for 3 research projects, 2 pilot research proj4ects, 1 pilot educational program, and core infrastructure at HUCC, along with additional funds for further planning and development of the HUCC/JHCCC partnership. Over the 5 years of support requested for the HUCC/JHCCC partnership, as these initial research and educational activities progress to compete for independent funding, new projects, programs, and resources of high priority for development will be identified and supported.