Generating haematopoietic stem cells from human pluripotent stem cells

从人类多能干细胞生成造血干细胞

• 批准号: nhmrc : 1129125
• 负责人: Prof Andrew Elefanty
• 金额: $ 59.5万
• 依托单位: Murdoch Childrens Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/generating-haematopoietic-stem-stem-cells/948352
• 关键词: Generating; haematopoietic; stem; cells; human

Blood stem cell transplantation is a vital therapy for patients with leukaemia following chemotherapy or for patients with bone marrow failure. Because many patients lack a donor, there is a need for an alternate source of stem cells. Using a new approach that we have developed, our laboratories will make blood stem cells from human pluripotent stem cells that will treat patients needing a transplant.

造血干细胞移植是白血病化疗后或骨髓衰竭患者的重要治疗方法。由于许多患者缺乏供体，因此需要替代干细胞来源。使用我们开发的新方法，我们的实验室将从人类多能干细胞中制造血液干细胞，用于治疗需要移植的患者。