Control of human ? cell differentiation and function

控制人类？

• 批准号: nhmrc : 1062268
• 负责人: Prof Andrew Elefanty
• 金额: $ 41.14万
• 依托单位: Murdoch Childrens Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/control-human-cell-differentiation-function/454975
• 关键词: Control; human; cell; differentiation; function

Diabetes is a condition in which the body is unable to regulate the level of glucose in the blood. Blood glucose is normally controlled by a particular cell type, the beta cell, which is found in the pancreas. In diabetes, this cell is either missing or does not function correctly. This project will produce human beta cells in the laboratory that can be used to find out what goes wrong in diabetes.

糖尿病是一种身体无法调节血液中葡萄糖水平的状况。血糖通常由一种特殊的细胞类型--β细胞控制，这种细胞存在于胰腺中。在糖尿病患者中，这种细胞要么缺失，要么不能正常工作。该项目将在实验室生产人类β细胞，可以用来找出糖尿病的问题所在。