Haematopoietic stem cells from human pluripotent stem cells: the future of bone marrow transplantation

来自人类多能干细胞的造血干细胞：骨髓移植的未来

• 批准号: nhmrc : 1117596
• 负责人: Prof Andrew Elefanty
• 金额: $ 52.22万
• 依托单位: Murdoch Childrens Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/haematopoietic-stem-cells-marrow-transplantation/946249
• 关键词: Haematopoietic; stem; cells; human; pluripotent

Blood stem cell transplantation is a vital therapy for patients with leukaemia following chemotherapy or for patients with bone marrow failure. Because many patients lack a donor, there is a need for an alternate source of stem cells. My laboratory will make blood stem cells from human pluripotent stem cells that will treat patients needing a transplant and will be a useful research tool to help us to understand what goes wrong in the blood system in a range of illnesses.

造血干细胞移植是白血病化疗后或骨髓衰竭患者的重要治疗方法。由于许多患者缺乏供体，因此需要替代干细胞来源。我的实验室将从人类多能干细胞中制造血液干细胞，用于治疗需要移植的患者，并将成为一个有用的研究工具，帮助我们了解血液系统在一系列疾病中出现的问题。