Endothelial development from pluripotent stem cells as a means to study pathology in Pulmonary Artery Hypertension

多能干细胞的内皮发育作为研究肺动脉高压病理学的手段

• 批准号: nhmrc : 1051339
• 负责人: Prof Andrew Elefanty
• 金额: $ 40.9万
• 依托单位: Murdoch Childrens Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/endothelial-development-pluripotent-artery-hypertension/112210
• 关键词: Endothelial; development; pluripotent; stem; cells

Pulmonary artery hypertension (PAH) is a fatal disease primarily affecting young adults. It is caused by a defect in cells that form the vessel that carries blood from the heart to the lungs. We will use stem cells made from the skin of PAH patients to examine why the blood vessel cells from these patients fail to function normally.

肺动脉高压（PAH）是一种主要影响年轻人的致命疾病。它是由形成将血液从心脏输送到肺部的血管的细胞缺陷引起的。我们将使用从多环芳烃患者的皮肤中提取的干细胞来检查为什么这些患者的血管细胞不能正常运作。