High-resolution elastography – Using optical micro-imaging of tissue mechanics to identify disease

高分辨率弹性成像 — 使用组织力学的光学显微成像来识别疾病

• 批准号: DP140104443
• 负责人: Prof David Sampson
• 金额: $ 44.38万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP140104443
• 关键词: resolution; elastography; Using; optical; micro

Optical elastography, the probing of tissue’s micro-mechanical properties using optical imaging, offers new tools in surgery and pathology to improve differentiation of tissues. This project lays the groundwork for optical elastography to become a new medical micro-imaging modality by removing impediments to progress in this rapidly emerging field. On the micro-scale, between the scales of cells and organs. This project will elucidate the origins of tissue mechanical contrast and determine limits on its measurement. It will develop a suite of probes: noncontact, endoscopic and needle, to enable access to all tissues in the body. To progress toward a new modality and inform our research, the project will test our tools on breast cancer tissues and burn scars.

光学弹性成像是利用光学成像探测组织的微观力学特性，为外科和病理学提供了新的工具，以提高组织的分化。该项目为光学弹性成像成为一种新的医学显微成像模式奠定了基础，消除了这一快速新兴领域的进展障碍。在微观尺度上，介于细胞和器官的尺度之间。这个项目将阐明组织力学对比度的起源，并确定其测量的限制。它将开发一套探针：非接触式，内窥镜和针头，以进入身体的所有组织。为了向新的模式发展并为我们的研究提供信息，该项目将在乳腺癌组织和烧伤疤痕上测试我们的工具。