2007 BARRIER FUNCTION OF MAMMALIAN SKIN GRC

描述(申请人提供)：关于哺乳动物皮肤屏障功能的戈登研究会议是一项两年一度的活动，计划于2007年8月5日至10日在罗德岛州的Salve Regina大学举行第十次会议。这次会议代表了关于哺乳动物屏障的主要国际研究论坛，并集中在两者的生物物理、生物学和临床方面。 表皮中正常和病变的屏障的形成和功能。这次会议总体上是全额超额认购，这使得接受来自学术界、工业界和政府的与会者的最佳组合成为可能。初级和高级科学家的比例相等(约40%为女性)，40%-50%的与会者来自海外。同以往的会议一样，正在协调一致地努力招募世界各地的发言者和与会者参加2007年会议，特别是来自东欧、亚洲和前苏联的发言者和与会者。2007年的会议提出了一种平衡的主题，单独的会议专门讨论：适应性和反应性屏障；角质层的形成和成熟；最大化和评估皮肤渗透的策略；新出现的表皮屏障功能；皮肤生物力学；影响或穿越皮肤屏障的后果；以及生活方式和屏障功能。此外，热门话题/青年调查员会议将包括从海报主持人中挑选的六至七名主持人。最后，为了补充本次会议的不同主题，计划在当晚举行三次招贴式会议，每次会议最多30次发言。NIAMS要求提供资金，以支持总支出的一部分；其余部分将由GRC组织提供的23,500美元赠款支持，另外还有额外的资金，主要用于支持与这次会议有关的最低限度的社会活动，以及向业界征集资金。2007年GRC关于哺乳动物皮肤屏障功能的会议将是一个重要的跨学科场所，在那里将分享该领域的最新信息和发展。这次会议承诺为哺乳动物屏障的起源和维护提供新的见解， 这有望为患有皮肤病和其他疾病的患者带来立竿见影的实际后果。

DESCRIPTION (provided by applicant): The Gordon Research Conference on Barrier Function of Mammalian Skin is a biennial event, scheduled for its tenth meeting from August 5-10, 2007 at Salve Regina University in Rhode Island. This conference represents the primary international research forum on the mammalian barrier, and is focused on the biophysical, biological, and clinical aspects of both normal and diseased barrier formation and function in the epidermis. This conference is generally fully- to oversubscribed, which makes it possible to accept an optimal mix of attendees from academics, industry and government. Junior and senior scientists are equally represented (approximately 40% females), with 40-50% of attendees are from overseas. As in prior meetings, a concerted attempt is being made to recruit speakers and attendees from around the world for the 2007 meeting, particularly from Eastern Europe, Asia, and the FSU (Former Soviet Union). The 2007 conference proposes a balance of topics with individual sessions devoted to: The adaptive and reactive barrier; Stratum corneum formation and maturation; Strategies to maximize and assess skin penetration; Emerging epidermal barrier functions; Skin biomechanics; Consequences of affecting or crossing the skin barrier; and, Lifestyle and barrier function. In addition, a Hot topics/Young investigators session will include six-to-seven presentators selected from poster presenters. Finally, to complement the diverse themes of this meeting, three poster sessions are scheduled for the evenings, with up to 30 presentations in each session. Funds are requested from NIAMS to support a portion of the total expenses; the remainder will be supported by a $23,500 grant from the GRC Organization, with additional sums, primarily to support foreign travel as well as the minimal social activities associated with this conference, being solicited from industry. The 2007 GRC meeting on Barrier Function of Mammalian Skin will be an important interdisciplinary venue, where the latest information and developments in this field will be shared. This conference promises to provide new insights into the origin and maintenance of the mammalian barrier, that will hopefully lead to immediate, practical consequences for patients with skin and other disorders.