2007 BARRIER FUNCTION OF MAMMALIAN SKIN GRC

描述（由申请人提供）：关于哺乳动物皮肤屏障功能的戈登研究会议是两年一次的活动，定于2007年8月5日至10日在罗得岛的Salve Regina大学举行第十次会议。本次会议代表了哺乳动物屏障的主要国际研究论坛，并侧重于生物物理，生物和临床方面， 表皮中正常和患病的屏障形成和功能。这个会议通常是完全超额认购，这使得它可以接受来自学术界，工业界和政府的与会者的最佳组合。初级科学家和高级科学家人数相等（约40%为女性），40 - 50%的与会者来自海外。与以前的会议一样，正在努力从世界各地，特别是从东欧、亚洲和前苏联招募发言者和与会者参加2007年的会议。2007年的会议提出了一个主题的平衡与个别会议专门：适应性和反应性屏障;角质层的形成和成熟;策略，以最大限度地提高和评估皮肤渗透;新兴的表皮屏障功能;皮肤生物力学;影响或穿越皮肤屏障的后果;和，生活方式和屏障功能。此外，一个热门话题/年轻的研究者会议将包括六到七个从海报主持人中选出的演讲者。最后，为了补充本次会议的各种主题，安排在晚上举行三场海报会议，每场会议最多有30场演讲。从NIAMS请求资金支持总费用的一部分;其余部分将由GRC组织提供的23，500美元赠款支持，额外的款项主要用于支持国外旅行以及与本次会议相关的最低限度的社会活动，正在向行业征求。2007年GRC哺乳动物皮肤屏障功能会议将是一个重要的跨学科场所，在那里将分享这一领域的最新信息和发展。这次会议有望为哺乳动物屏障的起源和维持提供新的见解， 这将有望为皮肤病和其他疾病患者带来直接的实际后果。

DESCRIPTION (provided by applicant): The Gordon Research Conference on Barrier Function of Mammalian Skin is a biennial event, scheduled for its tenth meeting from August 5-10, 2007 at Salve Regina University in Rhode Island. This conference represents the primary international research forum on the mammalian barrier, and is focused on the biophysical, biological, and clinical aspects of both normal and diseased barrier formation and function in the epidermis. This conference is generally fully- to oversubscribed, which makes it possible to accept an optimal mix of attendees from academics, industry and government. Junior and senior scientists are equally represented (approximately 40% females), with 40-50% of attendees are from overseas. As in prior meetings, a concerted attempt is being made to recruit speakers and attendees from around the world for the 2007 meeting, particularly from Eastern Europe, Asia, and the FSU (Former Soviet Union). The 2007 conference proposes a balance of topics with individual sessions devoted to: The adaptive and reactive barrier; Stratum corneum formation and maturation; Strategies to maximize and assess skin penetration; Emerging epidermal barrier functions; Skin biomechanics; Consequences of affecting or crossing the skin barrier; and, Lifestyle and barrier function. In addition, a Hot topics/Young investigators session will include six-to-seven presentators selected from poster presenters. Finally, to complement the diverse themes of this meeting, three poster sessions are scheduled for the evenings, with up to 30 presentations in each session. Funds are requested from NIAMS to support a portion of the total expenses; the remainder will be supported by a $23,500 grant from the GRC Organization, with additional sums, primarily to support foreign travel as well as the minimal social activities associated with this conference, being solicited from industry. The 2007 GRC meeting on Barrier Function of Mammalian Skin will be an important interdisciplinary venue, where the latest information and developments in this field will be shared. This conference promises to provide new insights into the origin and maintenance of the mammalian barrier, that will hopefully lead to immediate, practical consequences for patients with skin and other disorders.