Immunohematology/Transfusion Medicine Research Training

描述（由申请人提供）： 本提案旨在更新我们于2001年启动的免疫血液学和输血医学研究培训补助金。它为已经完成临床培训的MD和MD/PhD提供了一个高度组织化的场所，以便在这个代表性不足的领域获得丰富的研究经验，在教学框架内，目标是产生富有成效的医生科学家。T32还培养希望成为实验室医学博士临床科学家的博士，他们具有基础研究技能，并了解临床翻译需求。由耶鲁大学实验医学系赞助，它还提供了一个机会，只有医学博士候选人与最小的先前的研究经验，同时追求额外的学位，无论是研究医学博士或生物医学工程硕士。核心实验室的经验是进行与所有学员有一个专门的“培训委员会”（类似于研究生论文委员会）;特别研讨会系列补充核心经验。我们的跨学科教师包括来自7个不同主要部门的22位资金充足，经验丰富的导师，所有这些人都有着悠久的合作历史，其实验室在博士后MD，博士后博士和前博士的同时培训方面经验丰富。在T32的第一个周期，将有五名受训人员-两名已毕业，其余的正在受训。两名毕业生（1名医学博士，1名博士）都获得了学术教职-其中一人获得了K 08奖。在3个正在进行的（2个医学博士，1个博士）中，两个医学博士正在攻读更高的研究方向学位（1个研究医学博士，另一个是生物工程硕士）。有3名男子和2名妇女，一名学员是波多黎各血统。他们在4个不同的实验室工作，代表2个不同的部门。根据这一经验，我们要求将博士后培训名额从2个增加到4个--我们已经有了优秀的候选人，他们可能会在2008-09年占据所要求的4个名额。总的来说，包括其他资助机制的研究学员，我们的“更大”免疫血液学研究计划有32名学员。我们认为这个项目填补了耶鲁大学和全国的重要研究培训需求。(End摘要）

DESCRIPTION (provided by applicant): This proposal is for renewal of our research training grant in Immunohematology and Transfusion Medicine initiated in 2001. It provides a highly organized venue for MDs and MD/PhDs who have completed their clinical training to obtain an intense research experience in this underrepresented field, within a didactic framework, with the goal of generating productive physician-scientists. The T32 also trains PhDs who wish to become PhD clinician-scientists in Laboratory Medicine with skills in basic research combined with an understanding of clinical translational needs. Sponsored by the Yale Department of Laboratory Medicine, it also provides an opportunity for MD-only candidates with minimal prior research experience to simultaneously pursue an additional degree, either the Investigative Medicine PhD or a Master's in Biomedical Engineering. The core laboratory experience is carried out with all trainees having a dedicated 'training committee' (similar to a graduate student thesis committee); special seminar series complement the core experience. Our interdisciplinary faculty includes 22 well-funded, experienced mentors from 7 different primary departments, all of whom, have a long history of collaboration and whose laboratories are experienced in the simultaneous training of post-doc MDs, post-doc PhDs and pre-doc PhDs. In the first cycle of the T32, there will have been five trainees - two graduated and the remainder ongoing. Both graduates (1 MD, 1PhD) have obtained academic faculty positions - one has a K08 award. Of the 3 ongoing (2 MD, 1PhD), the two MDs are pursuing higher research-directed degrees (1 Investigative Medicine PhD, the other a Master's in Bioengineering). There are 3 men and 2 women, one trainee is of Puerto Rican heritage. They have worked in 4 different laboratories representing 2 distinct departments. Based on this experience, we are requesting an increase from 2 to 4 postdoctoral training slots - we already have excellent candidates in the pipeline who would potentially occupy the requested 4 slots through 2008-09. In total, including research trainees on other funding mechanisms, there are 32 trainees in our 'greater' immunohematology research program. We see this program as filling an important research training need both at Yale and nationally. (End of Abstract)