Microstructural imaging of the tumour microenvironment: towards virtual biopsy of prostate cancer

肿瘤微环境的微观结构成像：前列腺癌的虚拟活检

• 批准号: 2902117
• 金额: --
• 依托单位: CARDIFF UNIVERSITY
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2902117
• 关键词: Microstructural; imaging; tumour; microenvironment; towards

My project name is : Microstructural characterisation of the tumour environment : towards virtual biopsy of prostate cancer. I am trying to build an initial study acquiring non-invasive and comprehensive characterisation of the prostate gland. For my research I am using the most extensive MRI protocols at CUBRIC, Cardiff University, in its state-of-the-art Connectom scanners.For feature extraction, I am utilising the Spaarc radiomics pipeline, which is developed in the LIDA lab at the school of Engineering.I intend to acquire more MRI images in the near future, in patients with Prostate tumours to analyse the detection of cancer and translate computational models of underlying tissue microstructure like stroma content, vasculature, and epithelial cells, in the acquired high quality MR scans.

我的项目名称是：肿瘤环境的微观结构特征：前列腺癌的虚拟活检。我正在尝试建立一项初步研究，以非侵入性和全面的方式了解前列腺的特征。在我的研究中，我在卡迪夫大学 CUBRIC 的最先进的 Connectom 扫描仪中使用最广泛的 MRI 协议。对于特征提取，我使用在工程学院 LIDA 实验室开发的 Spaarc 放射组学管道。我打算在不久的将来在前列腺肿瘤患者中获取更多 MRI 图像，以分析癌症的检测并翻译底层组织的计算模型 在获得的高质量 MR 扫描中观察基质含量、脉管系统和上皮细胞等微观结构。