Microstructural imaging of the tumour microenvironment: towards virtual biopsy of prostate cancer

肿瘤微环境的微观结构成像：前列腺癌的虚拟活检

• 批准号: 2902117
• 金额: --
• 依托单位: CARDIFF UNIVERSITY
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2902117
• 关键词: Microstructural; imaging; tumour; microenvironment; towards

My project name is : Microstructural characterisation of the tumour environment : towards virtual biopsy of prostate cancer. I am trying to build an initial study acquiring non-invasive and comprehensive characterisation of the prostate gland. For my research I am using the most extensive MRI protocols at CUBRIC, Cardiff University, in its state-of-the-art Connectom scanners.For feature extraction, I am utilising the Spaarc radiomics pipeline, which is developed in the LIDA lab at the school of Engineering.I intend to acquire more MRI images in the near future, in patients with Prostate tumours to analyse the detection of cancer and translate computational models of underlying tissue microstructure like stroma content, vasculature, and epithelial cells, in the acquired high quality MR scans.

我的项目名称是：肿瘤环境的微观结构特征：迈向前列腺癌的虚拟活检。我正试图建立一个初步的研究，以获得前列腺的非侵入性和全面的特征。在我的研究中，我使用了卡迪夫大学CUBRIC最广泛的MRI协议，在其最先进的Connectom扫描仪中。对于特征提取，我使用的是由工程学院LIDA实验室开发的Spaarc放射组学流水线。我打算在不久的将来获得更多的MRI图像，在前列腺肿瘤患者中分析癌症的检测，并在获得的高质量MR扫描中翻译底层组织微观结构的计算模型，如基质含量，脉管系统和上皮细胞。