NRSA Hepatology Training Grant

描述（由申请人提供）： 这个应用程序是在加州大学旧金山分校的肝脏生物学和疾病的研究培训更新资金。理由是双重的：（1）该领域发展迅速，目前训练有素的研究人员数量不足，（2）加州大学旧金山分校在肝脏研究培训方面的资源和环境是例外。该计划位于胃肠病学部门，为寻求作为学术肝病学家职业的密集基础的学员提供两年的支持。它是跨学科的，包括流行病学和生物统计学系和肝移植计划，用于临床和结果研究，以及UCSF肝脏中心，用于实验室研究。导师组由来自医学、病理学、生物化学和微生物学/免疫学系的13名教员组成。所有人都有肝脏研究的研究项目，培训经验和合作记录。该计划由一个指导委员会监督，该委员会负责筛选申请人，投标报价和监督进度。入学申请将每年通过全国广告征集。最大的候选人库将是医学博士。申请人的研究者（研究密集型）轨道的UCSF亚专业计划在胃肠病学，但该过程将开放给其他人，包括博士。's.成功的申请人将有一个以出版物的形式取得成就的记录，在许多情况下，两个医学博士。和博士度申请人拥有博士学位学位只必须有一个强大的肝脏重点和方向转化研究。该计划的培训范围很广，从临床流行病学，遗传学，健康结果和政策，到细胞生物学，器官发生，免疫学，宿主-病原体相互作用和纤维化/致癌作用。与他们的研究相一致，学员提供基础和临床科学的正式指导，作为临床研究，生物医学科学和生物科学的UCSF研究生课程的一部分。一个核心课程，包括研究和有效的科学交流的道德行为是所有学生的必需。这项肝病学研究培训的毕业生将准备承担一个学院级的职位，并竞争个人的校外资助。

DESCRIPTION (provided by applicant): This application is for renewal funding of research training in liver biology and disease at UCSF. The rationale is two-fold: (1) the field is growing rapidly and currently has insufficient numbers of well-trained investigators, and (2) the resources and environment at UCSF for training in liver research are exceptional. The program, which is based in the Division of Gastroenterology, provides two years of support to trainees who seek an intensive grounding towards a career as academic hepatologists. It is inter-disciplinary, encompassing the Department of Epidemiology and Biostatistics and the Liver Transplant Program for those undertaking clinical and outcomes research, and the UCSF Liver Center for those engaged in laboratory-based research. The mentor group comprises 13 faculty from the Departments of Medicine, Pathology, Biochemistry and Microbiology/Immunology. All have research programs in liver research, experience in training, and a record of working together. The program is overseen by a Steering Committee, which is responsible for screening applicants, tendering offers, and monitoring progress. Applications for admission will be solicited annually by national advertisement. The largest candidate pool will be M.D. applicants to the Investigator (research-intensive) track of the UCSF subspecialty program in Gastroenterology, but the process will be open to others including Ph.D.'s. The successful applicant will have a record of accomplishment in the form of publications and, in many cases, both M.D. and Ph.D. degrees. Applicants with a Ph.D. degree only must have a strong liver focus and orientation to translational research. The range of training within the program is broad, from clinical epidemiology, genetics, health outcomes and policy, to cell biology, organogenesis, immunology, host-pathogen interactions and fibrosis/carcinogenesis. Coincident with their research, trainees are provided formal instruction in basic and clinical sciences as part of the UCSF graduate programs in Clinical Research, Biomedical Sciences and Biological Sciences. A core curriculum encompassing ethical conduct of research and effective scientific communication is required of all students. Graduates of this research training in hepatology will be ready to assume a faculty-level position and to compete for individual extramural funding.