Pediatric Nephrology Training Program

小儿肾脏病学培训计划

• 批准号: 7276760
• 负责人: ALLISON AUDREY EDDY
• 金额: $ 20.8万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7276760
• 关键词: Pediatric; Nephrology; Training; Program

DESCRIPTION (provided by applicant): The goal of this training program is to graduate physican-scientists to assume leadership roles in the field of academic Pediatric Nephrology. This is accomplished by an intense year of clinical training in all aspects of Pediatric Nephrology practice, supported by funds that are separate from this grant, followed by two-three years of comprehensive research training, either in basic science or clinical research. Trainees who complete the program are fully sub-board eligible in Pediatric Nephrology and expected to assume faculty positions at academic institutions and to begin the transition to independent investigative careers, usually via one of the mentored scientist programs. This program was developed in direct response to a critical manpower shortage in academic pediatric neprhology, which was/is coupled with the realization that most traditional pediatric nephrology training programs in this country are funded by clinical revenues and, therefore, provide inadequate research training in basic science and clinical investigation. It is estimaged that there is currently one pediatric nephrologist available in the U.S.A. for every 200,000 children. Comparatively, there are an estimated fourteen internist nephrologists per every 60,000 adults. Given recent significant advances in both molecular biology and clinical research, few traditional training programs in pediatric nephrology are presently designed to provide trainees with an opportunity to acquire substantive expertise with the methodologies and concepts of these disciplines. More than 6500 American children suffer from end-stage renal disease (ESRD), and many times that number are affected by chronic kidney disease. Currently, the entire ESRD program costs nearly $25 billion, with the federal government spending more than $17 billion. Despite these efforts, children receiving dialysis and transplantation have unacceptably high mortality rates, 3 times that of adults and more than 15% of the infant population. The reasons for this high mortality remain poorly defined, and, unfortunately, few studies are currently in progress to address this issue. Furthermore, it is now evident that many of the diseases that cause chronic kidney diseasse in adults begin in childhood. There is a pressing need to address these public health issues of kidney disease in children through research, and to train new physician-scientists to perform that critical work.

描述(由申请人提供)： 该培训计划的目标是培养物理学家，使其在儿科肾脏病学术领域担当领导角色。这是通过在儿科肾病实践的所有方面进行一年的密集临床培训来实现的，该培训由不同于这笔赠款的资金支持，然后是两到三年的基础科学或临床研究的综合研究培训。完成该计划的受训人员完全符合儿科肾病分会的资格，并有望在学术机构担任教职，并开始过渡到独立的研究职业生涯，通常是通过科学家导师计划之一。这项计划是为了直接应对儿科肾脏病学术人力短缺的严重问题而开发的，同时认识到这个国家的大多数传统儿科肾病培训计划都是由临床收入资助的，因此在基础科学和临床研究方面提供的研究培训不足。据估计，目前美国每200,000名儿童中就有一名儿科肾科医生。相比之下，据估计，每60,000名成年人中有14名内科肾病医生。鉴于最近在分子生物学和临床研究方面的重大进展，目前很少有儿科肾脏病的传统培训计划旨在为受训者提供机会，以获得这些学科的方法和概念的实质性专业知识。超过6500名美国儿童患有终末期肾病(ESRD)，而这一数字是慢性肾脏疾病的许多倍。目前，整个ESRD项目耗资近250亿美元，其中联邦政府支出超过170亿美元。尽管作出了这些努力，但接受透析和移植的儿童的死亡率高得令人无法接受，是成年人的3倍，占婴儿人口的15%以上。这种高死亡率的原因仍然没有明确的定义，不幸的是，目前几乎没有研究正在进行中，以解决这个问题。此外，现在很明显，许多导致成人慢性肾脏疾病的疾病始于儿童时期。迫切需要通过研究解决儿童肾脏疾病的这些公共卫生问题，并培训新的内科科学家来执行这项关键工作。