大规模并行脑成像-猫眼课题宝

大规模并行脑成像

批准号：

7341396

负责人：

MARK J SCHNITZER

金额：

$79.0万

依托单位：

STANFORD UNIVERSITY

依托单位国家：

美国

项目类别：

财政年份：

2007

资助国家：

美国

项目状态：

已结题

起止时间：

2007-09-30 至 2012-07-31

来源：

https://reporter.nih.gov/project-details/7341396

关键词：

Ablation Adult Affect Algorithms Alzheimer&apos s Disease Alzheimer&apos s disease model Amplifiers Animal Behavior Animal Model Animals Area Award Axon Back Behavior Behavior Disorders Behavioral Biological Models Biology Biomedical Engineering Biomedical Research Biomedical Technology Biotechnology Brain Brain Diseases Brain imaging Budgets Caenorhabditis elegans Caliber Cell physiology Cells Characteristics Childhood Chromosome Pairing Class Clinic Cocaine Collaborations Communities Complement Computer Simulation Computer Vision Systems Computer-Aided Design Condition Cornea Crack Cocaine Data Data Analyses Data Set Data Storage and Retrieval Dendrites Deposition Depth Development Developmental Biology Devices Disease Dissection Doctor of Philosophy Drosophila genus Drosophila melanogaster Electrical Engineering Electronics Elements Embryo Engineering Ensure Event Exhibits Face Failure Fiber Optics Figs - dietary Five-Year Plans Fluorescence Microscopy Foundations Functional Magnetic Resonance Imaging Funding Genome Genomics Goals Grant Green Fluorescent Proteins Growth Hand Head Heart Heating Hour Housing Human Human Resources Huntington Disease Image Imaging Techniques Imaging technology Individual Industry Invasive Invertebrates Knowledge Label Laboratories Larva Laser Scanning Microscopy Lasers Lead Learning Left Libraries Life Light Lobe Magnetic Resonance Mammals Manuals Mechanics Mediating Medical Methods Microscope Microscopy Modeling Motion Motor Neurons Movement Disorders Mus Nature Nematoda Nerve Degeneration Neurobiology Neurodegenerative Disorders Neurons Neurosciences Nucleotides Numbers Olfactory Receptor Neurons Operating Rooms Operative Surgical Procedures Ophthalmology Optics Outcome Paper Parkinson Disease Pathology Pattern Penetration Personal Satisfaction Pharmacologic Substance Photoreceptors Physics Physiologic pulse Physiological Pigments Preclinical Drug Evaluation Principal Investigator Process Property Proteins Proteomics Publishing Pulse taking Purpose Rate Reporter Research Research Personnel Resolution Resources Retina Risk Role Rotation Route Safety Sapphire Scanning Schools Science Screening procedure Senile Plaques Shapes Silicon Societies Solutions Specific qualifier value Specimen Speed Standards of Weights and Measures Stimulus Study models Surface Surgeon Symptoms Synapses Synchrotrons Syndrome System Systems Biology Tea Techniques Technology Testing Textbooks Time Tissues Today Training Triplet Multiple Birth Tube United States National Academy of Sciences United States National Institutes of Health Universities Variant Veterans Virion Vision Visual Visual Fields Visual Motion Visual system structure Work Zebrafish addiction age related base behavioral sensitization brain volume career cellular imaging commercialization computer science cost data acquisition day design desire developmental disease developmental neurobiology digital dopamine system dopaminergic neuron drug discovery essays experience fluorescence imaging fluorescence microscope fly genetic manipulation genetic strain high throughput screening high throughput technology in vivo innovation insight instrument instrumentation lens light microscopy light scattering member mouse genome mutant nanoscale nervous system disorder neural circuit neurogenetics novel novel therapeutics object motion optical imaging optical traps practical application prevent professor programs reconstruction relating to nervous system research study response selective expression sensory stimulus sensory system size structural biology success tool two-photon

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Mark J. Schnitzer, Ph.D., is an assistant professor of biological sciences and applied physics at Stanford University. He received a Ph.D. in physics from Princeton University in 1999. Schnitzer's goal is to understand the large-scale dynamics of neural circuits. Toward this end, his lab has invented a number of minimally invasive brain-imaging techniques based on fiber-optics and has been investigating mammalian neural circuits underlying locomotor coordination using a multidisciplinary approach that combines imaging, behavioral, anatomical, and computational studies. With his Pioneer Award, Schnitzer is pursuing an understanding of neural dynamics in the fruit fly, with a focus on neural circuits involved in sensorimotor decision-making. His multidisciplinary approach makes use of new technology for automated, laser-based tissue dissection and brain imaging in large numbers of flies, allowing him to perform innovative analyses of the biological basis for decision-making. Schnitzer's honors include fellowships from the Beckman, Klingenstein, Sloan, and Packard foundations and a Presidential Early Career Award for Scientists and Engineers.

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