Pesticides And Parkinson s Disease In The Agricultural H

挪威母婴研究是对挪威孕妇及其子女进行的一项队列研究。NIEHS正在为这一努力做出贡献，创建了一个生物标本库，以评估环境暴露和对孕妇及其未出生的孩子的健康影响。截至2006年7月31日，51,472名妇女为NIEHS研究部分提供了生物样本(血液和尿液)；本财政年度有16,000名妇女参加。这些样本已经在挪威各地的41家医院收集，包括城市中心和北极地区。招生目标是10万名女性。按照目前的招募速度，我们预计到2007年底，将有80000名妇女在怀孕17周时采集血液和尿液样本，以评估环境暴露情况。 在过去的一年里，我们出版了一份关于尿液储存和环境暴露(酚、邻苯二甲酸盐、非持久性杀虫剂)问题的手稿，并有一份关于生物标本库的手稿正在印刷中。与挪威调查人员合作，我们正在实施一项质量保证实验和方案，以评估各种参数的存储条件。在2004年10月的一次专业会议上介绍了初步质量保证措施的结果，目前正在编写一份手稿。

The Norwegian Mother and Child study is a cohort study of pregnant women and their children in Norway. NIEHS is contributing to this effort by creating of a biological specimen repository to evaluate environmental exposures and health effects to pregnant women and their unborn children. As of July 31, 2006, 51,472 women had contributed biological samples (blood and urine) for the NIEHS portion of the study; 16,000 women were enrolled this fiscal year. These samples have been collected at 41 hospitals across Norway including urban centers and the Arctic regions. The enrollment target is 100,000 women. At the current recruitment rate we anticipate 80,000 women with blood and urine samples collected at 17 weeks gestation to evaluate for environmental exposures by the end of 2007. During the past fiscal year, we published a manuscript on issues related to urine storage and environmental exposures (phenols, phthalates, non-persistent pesticides) and have a manuscript in press regarding the biological specimen bank. In collaboration with Norwegian investigators, we are implementing a quality assurance experiment and protocol to assess storage conditions for a variety of parameter. Results of the initial quality assurance measures were presented at a professional meeting in October 2004 and a manuscript is currently in preparation.