EATRIGHT FOLLOW UP STUDY

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Background: This pilot and feasibility study, currently underway and funded by the UAB Clinical Nutrition Research Center (CNRC), utilizes an observational cohort design to determine the long-term weight loss success of former EatRight participants who completed the program at least 1 year ago. The primary aim of this study is to determine the long-term effectiveness of EatRight in those whose last date of participation was 1-4 years ago; secondary aims are to understand the impact of fruit and vegetable intake on weight maintenance and the impact of weight loss maintenance on disease risk factors. Study question: We hypothesize that changes in weight, waist circumference and BMI during the 12-week EatRight intervention will be maintained within a 95% confidence interval (CI) of ? 40% of individuals at follow-up 1 to 4 years post-intervention. Secondary hypotheses state that, compared to a group of matched controls, those with maintenance of 50% of weight loss will have higher fruit and vegetable intake and better control of standard cardiovascular and metabolic disease risk factors. To date, 75 former EatRight participants have been assessed with markers of metabolic disease risk, body composition, and dietary intake. GCRC utilization: The purpose of this GCRC application is to support the addition of a control cohort to the study population, thereby allowing comparison of the outcomes over time. Study population: Control participants will be matched to current EatRight follow-up study participants by age, gender, weight, and height. Outcome measures: Control participants will receive the same measures as former EatRight participants, including weight, blood pressure, lipids, glucose, insulin, body composition with dual energy X-ray absorptiometry, and analysis of dietary intake from 4-day food records. Both cohorts will be followed longitudi