THE ADAPT HYPERTENSION STUDY

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Hypertension is both more common and more severe in African-Americans compared with Whites. The Dietary Approaches to Stop Hypertension (DASH) dietary pattern was proven to reduce hypertension in a randomized trial, and the effect was greatest for African-Americans. However, when translated into the real world, an effectiveness study of the DASH pattern revealed only modest blood pressure lowering benefit for African-Americans and no benefit for African American women, in particular. Using principles of formative analysis, we have developed a modified DASH dietary pattern intervention that is expected to be culturally appropriate for African-Americans. The primary aim for this study is to conduct a randomized, controlled trial to determine the effectiveness of the modified DASH dietary pattern in reducing blood pressure for a cohort of African-Americans with pre-hypertension or stage I hypertension compared to a usual care control group. We hypothesize that greater blood pressure reduction will be achieved using a culturally appropriate DASH diet intervention in a group of African-Americans with prehypertension to stage I hypertension compared to a usual care control group. Primary outcomes are change in systolic and diastolic BP at 6 months. Secondary outcomes include changes in fruit, vegetable, dairy, and fat intake.