Improving Weight Loss Outcomes in African Americans

描述（由申请人提供）： 候选人：Jamy D. Ard，医学博士，是积极的，并致力于涉及临床研究的学术生涯。他已经证明了他的能力，完成项目和独立工作在过去，并显示出必要的素质，成为一个富有成效的研究人员与教育和培训提供了这笔赠款。赞助商：W.蒂莫西加维，医学博士，营养科学系主任，有指导临床研究人员的长期记录。亚拉巴马大学伯明翰分校（UAB）临床营养研究中心主任大卫艾利森博士和综合临床研究中心（GCRC）实验室核心主任芭芭拉高尔博士将担任共同赞助商。杜克高血压中心主任Laura Svetkey博士也将作为共同发起人发挥关键作用，参与对Ard博士进展的正式评估，并就研究计划中提出的活动进行合作。工作环境：UAB提供深度和多样性的临床研究工作，以及支持K23应用所需的最先进的物理资源。本提案中将使用的具体资源包括UAB的NIH资助的临床营养研究中心、UAB Pittman GCRC、K30临床研究培训计划以及营养科学系内的研究设施和资源。调研：这个培训机会的建议是调查管理非裔美国人肥胖的最佳方法，结合行为和生理角度。该研究计划的具体目标包括确定非洲裔美国人减肥文化适当干预的关键组成部分，并描述强调水果，蔬菜，膳食纤维和低脂乳制品对非洲裔美国人心血管风险因素的饮食模式的生理影响。拟议的培训和研究将为Ard博士提供必要的技能和经验，以推动他的职业生涯成为非洲裔美国人等特殊人群肥胖症的独立调查员。

DESCRIPTION (provided by applicant): Candidate: Jamy D. Ard, MD, is motivated and committed to an academic career involving clinical research. He has demonstrated his ability to complete projects and work independently in the past, and shows the qualtities necessary to become a productive researcher with the education and training provided by this grant. Sponsors: W. Timothy Garvey, MD, Chairman of the Department of Nutrition Sciences, has as long track record of mentoring clinical researchers. Dr. David Allison, director of the University of Alabama at Birmingham (UAB) Clinical Nutrition Research Center, and Dr. Barbara Gower, Director of the General Clinical Research Center (GCRC) Laboratory Core, will serve as co-sponsors. Dr. Laura Svetkey, Director of the Duke Hypertension Center, will also play a pivotal role as co-sponsor by participating in formal appraisals of Dr. Ard's progress and collaborating on activities proposed in the research plan. Environment: UAB provides depth and diversity of clinical research endeavors as well as state-of-the-art physical resources necessary to support this K23 application. Specific resources that will be utilized in this proposal include UAB's NIH funded Clinical Nutrition Research Center, the UAB Pittman GCRC, the K30 Clinical Research Training Program, and research facilities and resources within the Department of Nutrition Sciences. Research: The proposal for this training opportunity is to investigate optimal ways to manage obesity in African Americans, combining behavioral and physiologic perspectives. The specific aims of the research plan include identifying key components of a culturally appropriate intervention for weight loss in African Americans and characterizing the physiologic effects of a dietary pattern that emphasizes fruits, vegetables, dietary fiber, and low-fat dairy products on cardiovascular risk factors in African Americans. The proposed training and research will provide Dr. Ard with the necessary skills and experience to advance his career to an independent investigator in obesity in special populations such as African Americans.