Continuous BP monitor for dialysis applications

用于透析应用的连续血压监测仪

基本信息

批准号：
7271794
负责人：
MARTIN Carl BARUCH
金额：
$ 9.96万
依托单位：
EMPIRICAL TECHNOLOGIES CORPORATION
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-06-04 至 2008-06-03
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7271794
关键词：
Address Affect Algorithms American Area Arrhythmia Arterial Lines Arteries Atrial Fibrillation Australia Back Blood Pressure Blood Pressure Monitors Blood flow Braces-Orthopedic appliances Breast Caliber Calibration Cardiac Cardiovascular Diseases Cardiovascular system Carotid Arteries Catheters Central Artery Cessation of life Characteristics Chronic Kidney Failure Class Clinical Research Colon Carcinoma Complex Condition Consent Coronary Angiography Coupled Couples Coupling Data Databases Descending aorta Development Device Designs Devices Diabetes Mellitus Dialysis patients Dialysis procedure Diastolic blood pressure Differential Mortality Distant Effectiveness Elevation End stage renal failure England Epidemiologic Studies Europe Excess Mortality Fistula Forearm Forehead General Population Gold Growth Hand Head Health Heart Heart Diseases Heart Rate Height Hemodialysis Hypertension Immunosuppression Individual Invasive Kidney Kidney Failure Kidney Transplantation Knowledge Lateral Light Masks Mattresses Measurement Measures Medical center Miniaturization Modeling Monitor Morphologic artifacts Movement Nephrology Noise North America Numbers Operative Surgical Procedures Organ Palpation Patient Monitoring Patients Performance Peripheral Phase Physical Dialysis Physiologic pulse Population Positioning Attribute Preparation Prevention strategy Procedures Process Prostate Protocols documentation Public Health Publishing Pulse Pressure Pulse taking Radial Randomized Controlled Trials Range Rate Reading Relative (related person)Renal function Research Risk Running Shapes Signal Transduction Site Staging Standards of Weights and Measures Stream Symptoms System Target Populations Techniques Technology Testing Therapeutic immunosuppression Thoracic aorta Time Toxic effect Transplant Recipients Travel United States Food and Drug Administration Universities Upper arm Validation Variant Virginia Wales Wireless Technology Work Wrist abdominal aorta aged base blood pressure regulation data acquisition data modeling design diabetic electric impedance improved instrument meter miniaturize neonate normotensive novel outcome forecast physical model pressure programs prototype radial artery renal artery research study response sensor size telemetering transmission process trend

项目摘要

DESCRIPTION (provided by applicant): The need for the continuous monitoring of blood pressure in patients undergoing dialysis is steadily increasing. While the population undergoing dialysis, presently at about 400k in the US, is growing along with the global growth in chronic kidney disease (CKD) patients, the general health of the dialysis population is declining as increasingly sicker patients undergo the very invasive procedure. In response ETC proposes to develop and test a wireless wrist-worn continuous blood pressure monitor that will permit the centralized monitoring of patients undergoing dialysis. The device is non-occlusive and utilizes a novel physical model of the radial pulse to determine BP via pulse analysis. The compact design of the device makes patient mobility and wireless connectivity possible. The device's effectiveness in comparison to gold standards will be tested in a clinical study involving 95 normotensive subjects as well as dialysis and kidney transplant patients.

描述（由申请人提供）：对接受透析的患者进行血压的持续监测的需求正在稳步增加。尽管目前在美国约40万的人群随着慢性肾脏疾病（CKD）患者的全球增长而增长，但随着透析人群的一般健康状况正在下降，因为越来越病的患者接受了非常侵入性的手术。在响应中，建议开发和测试无线腕部连续血压监测仪，该血压调节仪将允许对透析的患者进行集中监测。该设备是非熟悉的，并利用了径向脉冲的新型物理模型通过脉冲分析来确定BP。设备的紧凑设计使患者的移动性和无线连接成为可能。与黄金标准相比，该设备的有效性将在一项涉及95名正常血统受试者以及透析和肾脏移植患者的临床研究中进行测试。