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Study of the urokinase plasminogen activator signalling

Study of the urokinase plasminogen activator signalling
尿激酶纤溶酶原激活剂信号传导的研究
批准号:
7338826
负责人:
Jacek T Lubkowski
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
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英文摘要
The primary accomplishment was to solve the crystal structures of the complex between soluble part of the urokinase plasminogen activator receptor (suPAR) and the amino-terminal fragment of the urokinase plasminogen activator (ATF). This structures for the first time showed the details of interactions between ATF and suPAR, thus opening the path for rational development of inhibitors blocking these interactions.
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Studies of Proteins with Important Roles in Immunology andor Cancer Biology
  • 批准号:
    7592911
  • 项目类别:
  • 资助金额:
    $14.83万
  • 财政年份:
    --
  • 负责人:
    Jacek T Lubkowski
  • 依托单位:
Crystallographic Studies of Chemokines, Chemokine Recept
Studies of Proteins with Important Roles in Immunology andor Cancer Biology
  • 批准号:
    7965618
  • 项目类别:
  • 资助金额:
    $66.11万
  • 财政年份:
    --
  • 负责人:
    Jacek T Lubkowski
  • 依托单位:
Crystallographic Studies of Chemokines, Chemokine Recept
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