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PROTEINS UNDER PRESSURE

PROTEINS UNDER PRESSURE
压力下的蛋白质
批准号:
7357737
负责人:
SOL M GRUNER
金额:
$4.53万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2006
资助国家:
美国
项目状态:
已结题
起止时间:
2006-07-01 至 2007-06-30
关键词:

项目摘要

项目成果

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中文摘要
翻译
这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金,因此可能会出现在其他CRISE条目中。列出的机构是针对中心的,而不一定是针对调查员的机构。柑橘碱是一种黄色荧光蛋白,在压力下会变色。它的发射光谱红移了约4 nm,当它被加压到3.5kbar时,荧光强度下降了约10%。量子化学模拟表明,这可能是由于压力使蛋白质中的发光元件变形所致。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Citrine is a yellow fluorescent protein that changes color under pressure. Its emission spectrum redshifts by around 4 nm, and the intensity of the fluorescence drops by around 10% when it is pressurized to 3.5 kBar Quantum chemical modelling indicates that this might be due to deformation of the light emitting element in the protein by pressure.
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MACCHESS PROGRAM FOR PRESSURE CRYOCOOLING AND RELATED PROCEDURES
  • 批准号:
    8363544
  • 项目类别:
  • 资助金额:
    $1.14万
  • 财政年份:
    2011
  • 负责人:
    SOL M GRUNER
  • 依托单位:
DYNAMICS OF PROTEIN RNASE A & WATER-PROTEIN INTERACT AT DIFFERENT TEMPERATURES
  • 批准号:
    7955570
  • 项目类别:
  • 资助金额:
    $2.22万
  • 财政年份:
    2009
  • 负责人:
    SOL M GRUNER
  • 依托单位:
PRESSURE-INDUCED PROTEIN GLASS TRANSITION AND WATER-PROTEIN INTERACT
  • 批准号:
    7955589
  • 项目类别:
  • 资助金额:
    $5.49万
  • 财政年份:
    2009
  • 负责人:
    SOL M GRUNER
  • 依托单位:
MACCHESS PROGRAM FOR MICROCRYSTALLOGRAPHY/MEMBRANE PROTEIN CRYSTALS
  • 批准号:
    7955550
  • 项目类别:
  • 资助金额:
    $3.05万
  • 财政年份:
    2009
  • 负责人:
    SOL M GRUNER
  • 依托单位:
国内基金
海外基金
体硅下薄膜(TUB,Thinfilm Under Bulk)复合结构成型机理及其高性能器件研究