PREVENTION OF CHRONIC ASTHMA: AGE 7 FOLLOW-UP

预防慢性哮喘：7 岁随访

• 批准号: 7377739
• 负责人: Mary D. Klinnert
• 金额: $ 1.36万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7377739
• 关键词: PREVENTION; CHRONIC; ASTHMA; AGE; FOLLOW

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study investigates the efficacy of an early environmental with children at risk for asthma. In addition this study also investigates the natural history of asthma and the psychosocial and environmental issues surrounding childhood asthma in a low-income population. This proposal follows the progress of the subjects previously enrolled in the Childhood Asthma Prevention Study (CAPS). The subjects were enrolled because they had 3 or more physician-documented episodes of wheezing prior to the age of 2 and were from low-income families. Both of these factors put them at risk for childhood asthma. In the previous phase of the CAPS study, the families were randomized into two different intervention groups. Those families in the treatment condition had a nurse home-visitor work with them for a year on an asthma management protocol. The families in the information control group received written information about asthma management only. At four years of age, the children were assessed for asthma status. This proposal follows these children until the age of 7 years when asthma status will again be assessed to test the efficacy of the intervention. The families will be contacted to begin this follow-up when the children are 6 years old. The follow-up will then continue for a year until the children are 7 when they come into National Jewish for a medical evaluation.

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。本研究探讨早期环境对儿童哮喘风险的影响。此外，本研究还调查了哮喘的自然历史以及低收入人群中儿童哮喘的社会心理和环境问题。这项建议遵循了先前在儿童哮喘预防研究（CAPS）中登记的受试者的进展。受试者被纳入研究是因为他们在2岁之前有3次或更多的医生记录的喘息发作，并且来自低收入家庭。这两个因素都使他们有患儿童哮喘的风险。在CAPS研究的前一阶段，这些家庭被随机分为两个不同的干预组。那些处于治疗状态的家庭有一名护士家访，在哮喘管理协议上与他们一起工作一年。信息控制组的家庭只收到有关哮喘管理的书面信息。在四岁时，对儿童进行哮喘状况评估。该建议跟踪这些儿童直到7岁，届时将再次评估哮喘状况以测试干预措施的有效性。当孩子长到6岁时，我们会联系这些家庭开始后续调查。然后，随访将持续一年，直到孩子们7岁时，他们来到国家犹太医院进行医学评估。