UCLA MULTICENTER AIDS COHORT STUDY: NATURAL HISTORY OF AIDS IN HOMOSEXUAL MEN

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。多中心艾滋病队列研究是一项前瞻性队列研究，始于1984年，跟踪艾滋病毒血清阳性和血清阴性的男性。加州大学洛杉矶分校的艾滋病自然史研究是多中心艾滋病队列研究的四个中心之一。加州大学洛杉矶分校招收了1637名学生，全校共有5622名学生。目前约有1800名活跃科目报名。受试者每半年接受一次MACS范围的问卷调查，一系列神经心理学测试，一次简短的体检，以及常规的血液采集和可能的精液、唾液、尿液或大便样本的采集。NIAID为公开招聘提供了补充资金，以便提高统计能力，招收拉美裔和非洲裔少数群体以及年轻(39岁)的高加索男子，这些群体目前受艾滋病毒/艾滋病的影响最大，目的是招收反映当前流行病的族裔群体。据估计，海港GCRC的科目总数约为240人，他们每人每年将有两次访问EPR。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Multicenter AIDS Cohort Study is a prospective cohort study that was begun in 1984 to follow HIV seropositive and seronegative men. The UCLA Natural History of AIDS Study is one of four centers of the Multicenter AIDS Cohort Study. There are 1637 subjects enrolled at UCLA, and 5622 MACS-wide. There are now about 1800 active subjects enrolled. Subjects are followed semi-annually who undergo administration of the MACS-wide questionnaires, a battery of neuropsychologic tests, a brief physical examination, and the routine collection of blood and possible collection of semen, saliva, urine, or stool samples. Supplemental funding from NIAID was awarded to open recruitment in order to improve statistical power and enroll Latino and African-American minorities, as well as younger (<39 yrs) Caucasian men, the groups currently most affected by HIV/AIDS, with the goal of enrolling ethnic groups reflective of the current epidemic. Total enrollment of subjects at Harbor GCRC is estimated at about 240 men who will each have two visits epr year.