AN ANALYSIS OF CEREBRAL VASCULAR RESERVE IN PATIENTS WITH ANGIOPLASTY

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to evaluate for disease of the blood vessels. Patients who have had a stroke or brain hemorrhage are at risk for a condition known as "cerebral angiopathy", or abnormality of the blood vessels of the brain. For these patients, blood vessels may be impaired in such a manner that they are unable to expand and contract in order to meet the blood flow demands on the brain. This function is known as "cerebral autoregulation"and if it is impaired, a patient will have an increased risk of for future stroke. Patients who have had a TIA (transient ischemic attack or mini stroke)are less likely to have an impairment in the function of the blood vessels.