POLY MVA UTILIZED AS NEUROPROTEIN IN CHRONIC HYPERTENSION

聚 MVA 作为神经蛋白用于治疗慢性高血压

• 批准号: 7607888
• 负责人: CANDICE J PERKINS
• 金额: $ 1.12万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-23 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607888
• 关键词: Area; Blood Vessels; Brain; Cell Death; Cells; Chronic; Computer Retrieval of Information on Scientific Projects Database; Condition; Depth; Disease; Energy Supply; Energy Transfer; Funding; Grant; High Blood Pressure; Hypertension; Institution; Oxygen; Recording of previous events; Research; Research Personnel; Resources; Source; United States National Institutes of Health; brain cell; dietary supplements; prevent

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Some people with a history of high blood pressure develop hardening and reduced flow in the deep blood vessel of the brain. This results in areas of decreased oxygen delivery, which then results in decreased energy supply and possible brain cell death. This condition is called " Small Vessel Disease" (SVD) . There is no current FDA-approved treatment for this condition. We at Stony Brook have been studying the effects of a dietary supplement , Poly-MVA, as a protection against Small Vessel Disease. This supplement acts as an "energy boost" ; it has the ability to transfer energy to cells. We believe this may prevent cell death in vunerable areas.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 一些有高血压史的人会出现大脑深部血管硬化和血流减少。这导致氧气输送减少的区域，然后导致能量供应减少和可能的脑细胞死亡。这种情况被称为“小血管病”（SVD）。目前没有FDA批准的治疗这种疾病的方法。我们在斯托尼布鲁克一直在研究的影响，膳食补充剂，聚MVA，作为一种保护对小血管疾病。这种补充剂作为一种“能量提升”;它有能力将能量转移到细胞。我们相信这可以防止脆弱区域的细胞死亡。