OCCUPATION AND ASTHMA IN AN URBAN LOW INCOME POPULATION

城市低收入人群的职业与哮喘

• 批准号: 7378263
• 负责人: George Friedman-Jimenez
• 金额: $ 1.26万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7378263
• 关键词: OCCUPATION; ASTHMA; URBAN; LOW; INCOME

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Among adults in the United States, asthma has become a major public health problem, with rates most elevated among low-income, urban, African-American and Latino sectors of the population, and with substantial evidence suggesting potential occupational contributions to the excess rates. These important sectors of the U.S. population, however, have been inadequately represented in the occupational asthma research literature. A case-control study of physician-diagnosed asthma, occupation, industry, and workplace environmental exposures is proposed to evaluate the hypothesis that a substantial component of the asthma burden in a low-income, urban, largely-minority population is due to occupational factors. The objective of this study is to evaluate potential occupational contributions to incidence and morbidity of asthma in an urban, low-income, predominantly minority working population with high rates of asthma. This will be accomplished by conducting two linked studies of the patient population of Bellevue Hospital in New York City. The specific aims are as follows: 1) Conduct a case-control study of new-onset asthma to evaluate the hypothesis that a substantial fraction of incident asthma in the low-income, urban, largely-minority working population served by Bellevue Hospital is attributable to occupational causes. 2) Conduct a prevalence survey to estimate the fraction of prevalent asthma that is aggravated by factors at work, and a second case-control study to evaluate hypotheses of association between aggravation of asthma symptoms at work and specific occupations and workplace exposures.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。在美国的成年人中，哮喘已成为一个主要的公共卫生问题，在低收入、城市、非洲裔美国人和拉丁美洲人群体中发病率最高，大量证据表明职业可能导致发病率过高。然而，美国人口的这些重要部分在职业性哮喘研究文献中的代表性不足。一项病例对照研究，医生诊断的哮喘，职业，行业和工作场所的环境暴露，建议评估的假设，在低收入，城市，主要是少数民族人口的哮喘负担的一个重要组成部分是由于职业因素。 本研究的目的是评估在城市，低收入，主要是少数民族的工作人群哮喘发病率和发病率的潜在职业贡献。这将通过对纽约市贝尔维尤医院的患者人群进行两项相关研究来实现。具体目的如下：1）进行新发哮喘的病例对照研究，以评估Bellevue医院服务的低收入、城市、少数民族工作人群中哮喘事件的很大一部分可归因于职业原因的假设。2)进行一项患病率调查，以估计由工作中的因素加重的流行性哮喘的比例，并进行第二项病例对照研究，以评估工作中哮喘症状加重与特定职业和工作场所暴露之间的关联假设。