DNA MICROARRAY AND PROTEOMICS CORE

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。该核心的目的是为项目研究人员提供专家咨询，技术培训和最先进的仪器资源，以通过应用DNA微阵列分析和基于蛋白质的（“蛋白质组学”）方法来推进他们的研究工作。DNA微阵列分析组件将允许研究人员使用革命性的DNA微阵列筛选技术，通过应用Affyscore GeneChip筛选和先进的计算/统计分析方法进行全面的基因表达谱分析。蛋白质组学部分将为研究人员提供技术援助和仪器资源，以使用传统和尖端的蛋白质生物化学技术来解决蛋白质功能问题。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this core is to provide project investigators with a resource for expert consultation, technical training, and state-of-the-art instrumentation to enable advancement of their research efforts through the application of DNA microarray analysis and protein based ('proteomic') approaches. The DNA microarray analysis component will permit investigators to use the revolutionary DNA microarray screening technology to perform comprehensive gene expression profiling through application of Affymetrix GeneChip screening and advanced computational/statistical analysis methods. The proteomics component will provide investigators with technical assistance and instrumentation resources to use conventional and cutting edge protein biochemistry-based technologies to address questions of protein function.