PROTEOGENOMICS

蛋白质组学

• 批准号: 7959855
• 负责人: WILLIAM SCOTT ARGRAVES
• 金额: $ 23.22万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7959855
• 关键词: Address; Arts; Cardiovascular Diseases; Computer Retrieval of Information on Scientific Projects Database; Consultations; DNA Microarray Chip; Funding; Gene Expression Profiling; Grant; Institution; Methods; Microarray Analysis; Protein Biochemistry; Proteins; Proteomics; Research; Research Personnel; Resources; Screening procedure; Source; Surface; Technology; Training; United States National Institutes of Health; base; instrumentation; protein function

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this core is to provide project investigators with a resource for expert consultation, technical training, and state-of-the-art instrumentation to enable advancement of their research efforts through the application of DNA microarray analysis, qPCR and protein based ('proteomic') approaches. The DNA microarray analysis component permits investigators to use DNA microarray screening technology to perform comprehensive gene expression profiling through application of Affymetrix GeneChip screening and advanced computational/statistical analysis methods. The proteomics component provides investigators with technical assistance and instrumentation resources to use conventional and cutting edge protein biochemistry-based technologies including multiplex bead array and surface plasmon technology to address questions of protein function.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 该核心的目的是为项目研究人员提供专家咨询、技术培训和最先进仪器的资源，以便通过应用DNA微阵列分析、qPCR和基于蛋白质的（“蛋白质组学”）方法来推进他们的研究工作。DNA微阵列分析组件允许研究人员使用DNA微阵列筛选技术，通过应用Affyscore GeneChip筛选和先进的计算/统计分析方法进行全面的基因表达谱分析。蛋白质组学部分为研究人员提供技术援助和仪器资源，以使用传统和尖端的蛋白质生物化学技术，包括多重珠阵列和表面等离子体技术，以解决蛋白质功能的问题。