MS INBRE UMMC: GENOMICS FACILITY

MS INBRE UMMC：基因组学设施

• 批准号: 7381615
• 负责人: GEORGE M SANTANGELO
• 金额: $ 12.13万
• 依托单位: UNIVERSITY OF SOUTHERN MISSISSIPPI
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7381615
• 关键词: MS; INBRE; UMMC; GENOMICS; FACILITY

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Genomics Facility at UMC is a training facility that provides access to specialized equipment typically, but not entirely, associated with microarray technology. The genomics facility is seeing steady usage. The most active pieces of equipment being used are the Agilent bioanalyzer (for DNA and RNA analyses), the ScanArray Express scanner (microarray analysis) and the adjoining analytical computer and programs. Numerous labs throughout the Medical Center avail themselves of the facility on a regular basis. The facility also scans slides for other labs within the state that are not in the metro Jackson area. Presently, we are scanning catfish microarrays for Dr. Larry Hansen?s lab at Mississippi State University. We continue to introduce and train new labs in microarray technology. Although several facility users applied for grants this past year none were received. However we continue to do feasibility studies with several other labs which we hope can be garnered into fundable proposals. A proposal to study epigenetic effects of alcohol on zebrafish will be submitted within the current funding period. We have also agreed to beta-test some microarrays made by the University of Toronto Health Science network and W.L. Gore and Associates. Additionally we continue to demonstrate to pathology residents how RNA is labeled, hybridized and analyzed. Dr. Warren May, a Biostatistician in the Department of Preventive Medicine works with most of the groups doing microarray analysis through the facility. We require all groups wanting to use the facility to consult with him about the design of their experiments before beginning. Users are also encouraged to consult and collaborate with Dr. Youping Deng who is the bioinformatics expert at the University of Southern Mississippi and co-director of the bioinformatics branch of the MFGN. It is the goal of this facility to help facilitate the enhancement of the quality and quantity of research and life science training within the state of Mississippi through being available to all student and faculty researchers within the state; to train them in the methods and use of all of the equipment within the facility for their research. The facility is supervised by the director and facility manager and is available to all users at virtually anytime.

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中得到体现。列出的机构是中心的机构，不一定是研究者的机构。 UMC 的基因组学设施是一个培训设施，提供通常但不完全与微阵列技术相关的专用设备。基因组学设施的使用量稳定。使用的最活跃的设备是安捷伦生物分析仪（用于 DNA 和 RNA 分析）、ScanArray Express 扫描仪（微阵列分析）以及相邻的分析计算机和程序。医疗中心的许多实验室定期使用该设施。该设施还扫描幻灯片以查找该州内不在杰克逊地区的其他实验室。目前，我们正在为密西西比州立大学拉里·汉森博士的实验室扫描鲶鱼微阵列。我们继续引进和培训新的微阵列技术实验室。尽管一些设施用户去年申请了赠款，但没有收到任何赠款。然而，我们继续与其他几个实验室进行可行性研究，我们希望这些研究能够纳入可资助的提案中。研究酒精对斑马鱼表观遗传影响的提案将在当前资助期内提交。我们还同意对多伦多大学健康科学网络和 W.L. 制造的一些微阵列进行 Beta 测试。戈尔及其同事。此外，我们继续向病理住院医师演示如何标记、杂交和分析 RNA。 Warren May 博士是预防医学系的生物统计学家，与大多数通过该设施进行微阵列分析的小组合作。我们要求所有想要使用该设施的团体在开始之前就他们的实验设计咨询他。还鼓励用户向南密西西比大学生物信息学专家、MFGN生物信息学分会联席主任邓友平博士进行咨询和合作。该设施的目标是通过向密西西比州内的所有学生和教师研究人员开放，帮助提高密西西比州研究和生命科学培训的质量和数量；对他们进行研究方法和使用设施内所有设备的培训。该设施由主管和设施经理监督，几乎随时可供所有用户使用。