MS INBRE UM: PHARMOCOGENOMICS FACILITY

MS INBRE UM：药物基因组学设施

• 批准号: 7381616
• 负责人: GEORGE M SANTANGELO
• 金额: $ 18.92万
• 依托单位: UNIVERSITY OF SOUTHERN MISSISSIPPI
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7381616
• 关键词: MS; INBRE; UM; PHARMOCOGENOMICS; FACILITY

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. During the 2005-06 funding period the Pharmacogenomics/Toxicogenomic facility at the University of Mississippi has focused specifically on providing research infrastructure and support to the MFGN fellows as well as other researchers around the state in need of help getting started with fundable biomedical research programs. This has included visits by Fellows to this campus to encourage discussion and collaboration with respect to their research endeavors. We have recently hired a research scientist to oversee the Pharmacogenomics/Toxicogenomic facility who will be designing methods workshops for both in-person presentations and web access. ? The cadre of researchers associated with the Pharmacogenomics/Toxicogenomic facility at University of Mississippi provide one of the largest regional institutions of successfully NIH-funded biomedical researchers. This includes funded research projects from the following institutes: the National Center for Infectious Diseases (NCID), the National Institute of Allergy and Infectious Diseases (NIAID), the National Institute on Drug Abuse (NIDA), the National Cancer Institute (NCI), the National Center for Complementary & Alternative Medicine (NCCAM), the Fogarty International Center, and the National Institute of Environmental Health Sciences, which provides a wide base of knowledge and skills in that are being offered to help new investigators throughout the state. ? Expertise, equipment and infrastructure provided via the Pharmacogenomics/Toxicogenomic facility at University of Mississippi includes all aspects of drug discovery and development, automated DNA and oligonucleotide sequencing capabilities, development of drug screening technologies (antimicrobial, anticancer, etc.), RT-PCR technologies, Affymetrix microarray technology, separations technologies (LCMS, HPLC, LPLC, etc.), spectroscopy technologies (1D & 2D-NMR, ELS, UV-VIS, etc.) fermentation and cell biology technologies, environmental toxicology, etc.

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。在2005-2006年的资助期间，密西西比大学的药物基因组学/毒理基因组学设施专门致力于向MFGN研究员以及全州其他需要帮助的研究人员提供研究基础设施和支持，以启动可资助的生物医学研究计划。这包括研究员访问这个校园，以鼓励关于他们的研究努力的讨论和合作。我们最近聘请了一名研究科学家来监督药物基因组学/毒理基因组学设施，他将为面对面演示和网络访问设计方法研讨会。？与密西西比大学药物基因组学/毒理基因组学设施相关的研究人员队伍为成功地由NIH资助的生物医学研究人员提供了最大的地区性机构之一。这包括由以下机构资助的研究项目：国家传染病中心(NCID)、国家过敏和传染病研究所(NIAID)、国家药物滥用研究所(NIDA)、国家癌症研究所(NCI)、国家补充和替代医学中心(NCCAM)、福格蒂国际中心和国家环境健康科学研究所，后者提供了广泛的知识和技能基础，以帮助全州的新调查人员。？通过密西西比大学的药物基因组学/毒理基因组学设施提供的专业知识、设备和基础设施包括药物发现和开发的方方面面、自动化DNA和寡核苷酸测序能力、药物筛选技术(抗菌剂、抗癌等)的开发、RT-PCR技术、Affymetrix微阵列技术、分离技术(LC MS、HPLC、LPLC等)、光谱技术(一维和二维核磁共振、ELS、UV-Vis等)。发酵和细胞生物技术、环境毒理学等。