500 MHz NMR Spectrometer to Support Organic, Bio-organic and Inorganic Chemistry

支持有机、生物有机和无机化学的 500 MHz NMR 波谱仪

• 批准号: EP/D04779X/1
• 负责人: Mike Whittlesey
• 金额: $ 51.45万
• 依托单位: University of Bath
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2006
• 资助国家: 英国
• 起止时间: 2006 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FD04779X%2F1
• 关键词: 500; MHz; NMR; Spectrometer; Support

NMR spectroscopy is a key tool in the elucidation of chemical structure. A new NMR spectrometer operating at higher field (500 MHz) than currently available is required by a group of synthetic chemists interested in organic, bio-organic and inorganic chemistry. This spectrometer will facilitate new research areas in the Department of Chemistry at Bath by providing access to NMR facilities with (a) high sensitivity (somewhere in the region of a 40% increase over our current 400 MHz NMR spectrometer will be provided), (b) greater resolution that will allow resonances from more complex molecules to be separated out and (c) new hardware (for example, lower frequency nuclei can be studied, while an inverse detection probe will give higher proton sensitivity, allowing compounds only available in very small amounts to be characterised and and their structures established). Specific areas that will be enabled include the synthesis of chiral molecules, modification of peptides and proteins and the development of new catalysts.

核磁共振波谱是化学结构分析的重要工具。一群对有机、生物有机和无机化学感兴趣的合成化学家需要一种比目前可用的更高场（500 MHz）的新型核磁共振光谱仪。该光谱仪将促进巴斯大学化学系的新研究领域，通过提供核磁共振设备(a)高灵敏度（比我们目前的400 MHz核磁共振光谱仪将增加40%），(b)更高的分辨率，将允许从更复杂的分子中分离出共振，(c)新的硬件（例如，可以研究低频核）。而反向探测探针将提供更高的质子灵敏度，允许仅在非常少量可用的化合物进行表征并建立其结构)。具体领域将包括手性分子的合成、多肽和蛋白质的修饰以及新催化剂的开发。

项目成果

Photochemistry of Cp'Mn(CO) 2 (NHC) (Cp' = ? 5 -C 5 H 4 Me) Species: Synthesis, Time-Resolved IR Spectroscopy, and DFT Calculations

CpMn(CO) 2 (NHC) (Cp = ? 5 -C 5 H 4 Me) 物种的光化学：合成、时间分辨红外光谱和 DFT 计算

• DOI: 10.1021/om300209a
• 发表时间: 2012
• 期刊: Organometallics
• 影响因子: 2.8
• 作者: Batool M

The influence of N-heterocyclic carbenes (NHC) on the reactivity of [Ru(NHC)(4)H](+) with H(2), N(2), CO and O(2).

N-杂环卡宾 (NHC) 对 [Ru(NHC)(4)H]( ) 与 H(2)、N(2)、CO 和 O(2) 反应性的影响。

• DOI: 10.1002/chem.200901736
• 发表时间: 2009
• 期刊: Chemistry (Weinheim an der Bergstrasse, Germany)
• 作者: Burling S

Cationic tris N-heterocyclic carbene rhodium carbonyl complexes: Molecular structures and solution NMR studies

• DOI: 10.1021/om060202p
• 发表时间: 2006-05-08
• 期刊: ORGANOMETALLICS
• 影响因子: 2.8
• 作者: Burling, Suzanne;Douglas, Susie;Whittlesey, Michael K.
• 通讯作者: Whittlesey, Michael K.

Comparison of the photochemistry of organometallic N-heterocyclic carbene and phosphine complexes of manganese.

有机金属N-杂环卡宾和锰膦配合物的光化学比较。

• DOI: 10.1039/c1cc14467g
• 发表时间: 2011
• 期刊: Chemical communications (Cambridge, England)
• 作者: Batool M

Ring-Expanded N-Heterocyclic Carbene Complexes of Ruthenium

• DOI: 10.1021/om901044u
• 发表时间: 2010-02-22
• 期刊: ORGANOMETALLICS
• 影响因子: 2.8
• 作者: Armstrong, Robert;Ecott, Christopher;Whittlesey, Michael K.
• 通讯作者: Whittlesey, Michael K.