Molecular Surgeon Symposium on Genetics and Genomics of Pancreatic Cancer

分子外科医生胰腺癌遗传学和基因组学研讨会

• 批准号: 7408620
• 负责人: Changyi Chen
• 金额: $ 0.5万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-03-01 至 2009-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7408620
• 关键词: Award; Clinical; Data; Diagnosis; Discipline; Funding; Future; Gene Expression Alteration; Gene Expression Regulation; General Population; Genetic; Genomics; Goals; Housing; Institution; Journals; Malignant neoplasm of pancreas; Manuscripts; Medical Students; Medical center; Medicine; Molecular; Mucins; Neuropilins; Operative Surgical Procedures; Participant; Pathogenesis; Physicians; Postdoctoral Fellow; Publications; RAS genes; Request for Applications; Research; Research Personnel; Scientific Advances and Accomplishments; Scientist; Series; Students; Surgeon; Texas; Time; Travel; abstracting; anticancer research; college; concept; cost; day; interest; member; mesothelin; mouse model; posters; symposium

DESCRIPTION (provided by applicant): This R13 application requests funds to partially (50%) support the Molecular Surgeon Symposium on Genetics and Genomics of Pancreatic Cancer, which will be the fourth time of the Molecular Surgeon Symposium series in the Baylor College of Medicine (BCM). The symposium will be held at the Texas Medical Center, Houston, Texas, on April 12 and 13, 2008. The overall goal of this interdisciplinary scientific symposium is to bring together scientists and physicians from diverse fields with a common interest in understanding Genetics and Genomics of Pancreatic Cancer. It will also provide a unique opportunity for trainees (postdoctoral fellows, clinical residents and fellows, medical students, and other scientists) to interact with investigators in the field of cancer research. This symposium is unique in that it will provide a forum for presenting and discussing the latest advances in pancreatic cancer research. This one and a half day symposium will consist of an opening keynote presentation with the following scientific sessions: 1). Genomic alterations in pancreatic cancer; 2). Gene expression alteration in pancreatic cancer; 3). Gene regulation and functions in pancreatic cancer-I (mouse model and k-ras gene); and 4). Gene regulation and functions in pancreatic cancer-II (Smad, XIST, CACAM6, mucin, mesothelin, SSTR, neuropilins, and PDX-1). In addition, poster session will be organized. Attendees will be invited to submit an abstract to poster section planned for the symposium that will allow all attendees, especially students, residents, and young investigators, to present their data and fully participate in discussions. We anticipate approximately 250 attendees. The limited attendance, focused scientific sessions, and highly successful poster session combined will provide an exciting forum for the exchange of ideas and will provide extensive opportunities for participation by a diverse group of scientists interested in pancreatic cancer. Funding is requested for planning and organizing the meeting and for travel and housing costs for speakers and those trainees selected for travel awards. Matching funds (50%) will be provided by the Institution to cover other costs. The Organizing/Scientific Committee will consist of members from research disciplines that represent the integrated/educational concept of the Symposium. At the conclusion of the symposium, participants should be able to: 1) understand the impact and opportunities of genetics and genomics on pancreatic cancer research; 2) discuss recent scientific advances related to molecular pathogenesis, diagnosis, and therapy for pancreatic cancer; 3) determine the future directions of pancreatic cancer research; and 4) establish a collaborative network in pancreatic cancer research. All presentations will be video-taped and presented on the "The Molecular Surgeon" website for general public access (website has been established since 1999). Furthermore, invited speakers are encouraged to submit manuscripts related to their presentations to "World Journal of Surgery" for consideration of publications.

描述（由申请人提供）：此R13申请要求资金部分（50%）支持胰腺癌遗传学和基因组学分子外科医生研讨会，这将是贝勒医学院（Baylor College of Medicine）分子外科医生研讨会系列的第四次。 研讨会将于2008年4月12日和13日在德克萨斯州休斯顿的德克萨斯医学中心举行。 这个跨学科科学研讨会的总体目标是汇集来自不同领域的科学家和医生，共同关注胰腺癌的遗传学和基因组学。 它还将为学员（博士后研究员，临床住院医生和研究员，医学生和其他科学家）提供一个独特的机会，与癌症研究领域的研究人员进行互动。 本次研讨会是独一无二的，因为它将提供一个论坛，介绍和讨论胰腺癌研究的最新进展。 这个为期一天半的研讨会将包括一个开幕式主题演讲和以下科学会议：1）。胰腺癌中的基因组改变; 2）。胰腺癌中基因表达的改变; 3）.胰腺癌中的基因调控和功能-I（小鼠模型和k-ras基因）;和4）。胰腺癌中的基因调控和功能-II（Smad、XIST、CACAM 6、粘蛋白、间皮素、SSTR、神经纤毛蛋白和PDX-1）。 此外，还将举办海报展示会。 与会者将被邀请提交一份摘要到研讨会计划的海报部分，这将允许所有与会者，特别是学生，居民和年轻的研究人员，展示他们的数据，并充分参与讨论。 预计约有250人参加。 有限的出席人数，集中的科学会议，以及非常成功的海报会议相结合，将为交流思想提供一个令人兴奋的论坛，并将为对胰腺癌感兴趣的不同科学家群体提供广泛的参与机会。 要求提供资金，用于规划和组织会议，并支付演讲者和获选获得旅费奖励的受训人员的旅费和住宿费。 学院将提供等额资金（50%），以支付其他费用。 组织/科学委员会将由代表专题讨论会综合/教育概念的研究学科的成员组成。 在研讨会结束时，与会者应该能够：1）了解遗传学和基因组学对胰腺癌研究的影响和机会; 2）讨论与胰腺癌分子发病机制，诊断和治疗相关的最新科学进展; 3）确定胰腺癌研究的未来方向; 4）建立胰腺癌研究的合作网络。 所有的演讲都将被录像，并在“分子外科医生”网站上展示，供公众访问（网站自1999年以来一直在建立）。 此外，鼓励受邀演讲者向《世界外科杂志》提交与其演讲有关的手稿，以供考虑出版。

项目成果

Improved diagnosis of pancreatic adenocarcinoma using haptoglobin and serum amyloid A in a panel screen.

• DOI: 10.1007/s00268-008-9853-9
• 发表时间: 2009-04
• 期刊: WORLD JOURNAL OF SURGERY
• 影响因子: 2.6
• 作者: Firpo, Matthew A.;Gay, David Z.;Granger, Steven R.;Scaife, Courtney L.;DiSario, James A.;Boucher, Kenneth M.;Mulvihill, Sean J.
• 通讯作者: Mulvihill, Sean J.

Profiling of 95 microRNAs in pancreatic cancer cell lines and surgical specimens by real-time PCR analysis.

• DOI: 10.1007/s00268-008-9833-0
• 发表时间: 2009-04
• 期刊: WORLD JOURNAL OF SURGERY
• 影响因子: 2.6
• 作者: Zhang, Yuqing;Li, Min;Wang, Hao;Fisher, William E.;Lin, Peter H.;Yao, Qizhi;Chen, Changyi
• 通讯作者: Chen, Changyi

MicroRNAs: control and loss of control in human physiology and disease.

• DOI: 10.1007/s00268-008-9836-x
• 发表时间: 2009-04
• 期刊: WORLD JOURNAL OF SURGERY
• 影响因子: 2.6
• 作者: Li, Min;Marin-Muller, Christian;Bharadwaj, Uddalak;Chow, Kwong-Hon;Yao, Qizhi;Chen, Changyi
• 通讯作者: Chen, Changyi

Current understanding and potential immunotherapy for HIV-associated squamous cell carcinoma of the anus (SCCA).

• DOI: 10.1007/s00268-008-9835-y
• 发表时间: 2009-04
• 期刊: WORLD JOURNAL OF SURGERY
• 影响因子: 2.6
• 作者: Marin-Muller, Christian;Li, Min;Chen, Changyi;Yao, Qizhi
• 通讯作者: Yao, Qizhi