Molecular Surgeon Symposium on Genetics and Genomics of Pancreatic Cancer

描述(申请人提供)：此R13申请申请资金部分(50%)支持胰腺癌遗传学和基因组学分子外科医生研讨会，这将是贝勒医学院(BCM)分子外科医生研讨会系列的第四次。研讨会将于2008年4月12日和13日在德克萨斯州休斯敦的德克萨斯医疗中心举行。这次跨学科科学研讨会的总体目标是将来自不同领域的科学家和医生聚集在一起，对了解胰腺癌的遗传学和基因组学有共同的兴趣。它还将为受训人员(博士后研究员、临床住院医师和研究员、医学生和其他科学家)提供一个与癌症研究领域的研究人员互动的独特机会。这次研讨会的独特之处在于，它将为介绍和讨论胰腺癌研究的最新进展提供一个论坛。 这次为期一天半的研讨会将包括以下科学会议的开幕式主题报告：1)。胰腺癌的基因组改变；胰腺癌基因表达的改变；胰腺癌-I(小鼠模型和k-ras基因)中的基因调控和功能；胰腺癌-II(Smad、XIST、CACAM6、粘蛋白、间皮蛋白、SSTR、神经粘蛋白和PDX-1)的基因调控和功能。此外，还将组织招贴会。 与会者将被邀请向研讨会计划的海报部分提交摘要，该部分将允许所有与会者，特别是学生、居民和年轻研究人员，展示他们的数据并充分参与讨论。我们预计将有大约250人参加。有限的出席人数、集中的科学会议和非常成功的海报会议相结合，将为思想交流提供一个令人兴奋的论坛，并将为对胰腺癌感兴趣的不同科学家群体提供广泛的参与机会。请拨经费以规划和组织会议，并支付演讲者和被选为旅费奖受训人员的旅费和住宿费。该机构将提供配套资金(50%)，以支付其他费用。组织/科学委员会将由代表专题讨论会综合/教育概念的研究学科的成员组成。在研讨会结束时，与会者将能够：1)了解遗传学和基因组学对胰腺癌研究的影响和机遇；2)讨论与胰腺癌分子发病机制、诊断和治疗相关的最新科学进展；3)确定胰腺癌研究的未来方向；4)建立胰腺癌研究的合作网络。所有报告都将被录制下来，并在“分子外科医生”网站(该网站自1999年建立以来)上供公众查阅。此外，还鼓励被邀请的演讲者向《世界外科杂志》提交与其演讲相关的手稿，以供出版物审议。

DESCRIPTION (provided by applicant): This R13 application requests funds to partially (50%) support the Molecular Surgeon Symposium on Genetics and Genomics of Pancreatic Cancer, which will be the fourth time of the Molecular Surgeon Symposium series in the Baylor College of Medicine (BCM). The symposium will be held at the Texas Medical Center, Houston, Texas, on April 12 and 13, 2008. The overall goal of this interdisciplinary scientific symposium is to bring together scientists and physicians from diverse fields with a common interest in understanding Genetics and Genomics of Pancreatic Cancer. It will also provide a unique opportunity for trainees (postdoctoral fellows, clinical residents and fellows, medical students, and other scientists) to interact with investigators in the field of cancer research. This symposium is unique in that it will provide a forum for presenting and discussing the latest advances in pancreatic cancer research. This one and a half day symposium will consist of an opening keynote presentation with the following scientific sessions: 1). Genomic alterations in pancreatic cancer; 2). Gene expression alteration in pancreatic cancer; 3). Gene regulation and functions in pancreatic cancer-I (mouse model and k-ras gene); and 4). Gene regulation and functions in pancreatic cancer-II (Smad, XIST, CACAM6, mucin, mesothelin, SSTR, neuropilins, and PDX-1). In addition, poster session will be organized. Attendees will be invited to submit an abstract to poster section planned for the symposium that will allow all attendees, especially students, residents, and young investigators, to present their data and fully participate in discussions. We anticipate approximately 250 attendees. The limited attendance, focused scientific sessions, and highly successful poster session combined will provide an exciting forum for the exchange of ideas and will provide extensive opportunities for participation by a diverse group of scientists interested in pancreatic cancer. Funding is requested for planning and organizing the meeting and for travel and housing costs for speakers and those trainees selected for travel awards. Matching funds (50%) will be provided by the Institution to cover other costs. The Organizing/Scientific Committee will consist of members from research disciplines that represent the integrated/educational concept of the Symposium. At the conclusion of the symposium, participants should be able to: 1) understand the impact and opportunities of genetics and genomics on pancreatic cancer research; 2) discuss recent scientific advances related to molecular pathogenesis, diagnosis, and therapy for pancreatic cancer; 3) determine the future directions of pancreatic cancer research; and 4) establish a collaborative network in pancreatic cancer research. All presentations will be video-taped and presented on the "The Molecular Surgeon" website for general public access (website has been established since 1999). Furthermore, invited speakers are encouraged to submit manuscripts related to their presentations to "World Journal of Surgery" for consideration of publications.