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CRAFT Behavior Therapy Phase 2 Study: Tx Entry Component

CRAFT 行为疗法第二阶段研究：Tx 进入组件

基本信息

批准号：
7487088
负责人：
KIMBERLY C KIRBY
金额：
$ 52.09万
依托单位：
TREATMENT RESEARCH INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
起止时间：
2004-09-30 至 2010-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7487088
关键词：
Abstinence Aftercare Behavior Behavior Therapy Behavioral Caring Clinical Research Communities Controlled Clinical Trials Domestic Violence Drug abuse Drug usage Drug user Early Intervention Educational Intervention Educational process of instructing Family Family member Funding Goals Grant Health Personnel Illicit Drugs Intervention Laboratories Learning Length Manuals Moods National Institute of Drug Abuse Outcome Patients Pharmaceutical Preparations Phase II Clinical Trials Prevalence Principal Investigator Probability Procedures Psychological reinforcement Public Health Randomized Research Sampling Services Social Reinforcement Societies Staging Techniques Testing Training Treatment Efficacy Work alcohol abstinence base contingency management cost design drug abstinence drug abuser improved problem drinker programs reinforcer social therapy development voucher

项目摘要

The consequences of drug abuse are not limited to drug users; they also extend to their families and concerned significant others (CSOs). Research shows that CSOs of drug users have increased prevalence of illness, domestic violence, and problems in mood and functioning. Behavior therapy interventions, such as contingency management (CM) and the community reinforcement approach (CRA) have been among the most effective treatments for drug abuse. Financially-based CM is not well accepted by treatment providers, but our research indicates that social reinforcers are widely accepted. Because CSOs are troubled by the negative effects of drug use on the drug user and themselves, they may be a social community that is particularly invested in learning and implementing social reinforcers through CRA. In this application, we propose Stage II Behavior Therapy Development research on an intervention for CSOs known as Community Reinforcement and Family Training (CRAFT). This intervention teaches CSOs how to implement CRA, increasing the likelihood that the drug user will enter treatment and reduce drug use and improving CSO mood and functioning. Previous research conducted by Meyers, Miller and the principal investigator has accomplished the goals of Stage I research, including operationally defining and standardizing principles and techniques of CRAFT in manuals. In addition, early Stage II research demonstrated the efficacy of the therapy in three controlled clinical trials (Kirby et al., 1999; Meyers et al., 2002; Miller et al., 1999). This Stage II project will replicate previous findings and identify and explore the active components of CRAFT. Specifically, we will use a randomized controlled 2x2 design that will allow us to determine if the Treatment Entry Training (TENT) component is necessary and sufficient to produce the primary and most consistent outcome of CRAFT -- treatment entry of the drug user. The main contributions of exploring the components of CRAFT will be twofold. First, identifying effective components of treatment can help focus subsequent studies of mechanisms of action, improving our scientific understanding and possibly leading to improvements in the quality of the intervention and second, identifying ineffective components of CRAFT can help reduce its length and cost, making a behavioral intervention that is already acceptable even more community-friendly. Thus, the proposed research will have both scientific and practical benefits for drug users and their CSOs.

药物滥用的后果不仅限于吸毒者，还波及其家庭，重要他人（CSO）。研究表明，吸毒者的民间社会组织增加了流行率，疾病，家庭暴力，以及情绪和功能问题。行为治疗干预，如作为应急管理（CM）和社区强化方法（CRA），最有效的药物滥用治疗方法以经济为基础的CM不太被治疗所接受供应商，但我们的研究表明，社会化广告被广泛接受。因为公民社会组织由于吸毒对吸毒者和他们自己的负面影响，他们可能是一个社会社区，特别是投资于学习和实施通过CRA的社会责任。在这项申请中，我们提出了第二阶段行为治疗发展研究的干预，被称为社区强化和家庭培训的民间社会组织。这种干预教导民间社会组织如何实施CRA，增加吸毒者接受治疗并减少吸毒的可能性使用和改善CSO情绪和功能。Meyers、米勒和首席研究员已经完成了第一阶段研究的目标，包括操作定义和在手册中规范CRAFT的原理和技术。此外，早期第二阶段研究在三个对照临床试验中证明了该疗法的功效（Kirby等，1999; Meyers等人， 2002;米勒等人，1999年）。这个第二阶段项目将复制以前的研究结果，并确定和探讨 CRAFT的活动组件。具体而言，我们将使用随机对照2x2设计，我们确定治疗入门培训（TENT）部分是否必要且足以产生 CRAFT的主要和最一致的结果--吸毒者的治疗输入。主要探索CRAFT组件的贡献将是双重的。第一，确定有效成分可以帮助关注后续的作用机制研究，提高我们的科学理解并可能导致干预质量的改善，第二，识别CRAFT的无效组件可以帮助减少其长度和成本，已经可以接受的干预措施，甚至更有利于社区。因此，拟议的研究将对吸毒者和他们的民间社会组织都有科学和实际的好处。