Host metabolism and responses contributing to flavivirus replication and pathogenesis

宿主代谢和反应有助于黄病毒复制和发病机制

• 批准号: nhmrc : 1081786
• 负责人: A/Pr Jason Mackenzie
• 金额: $ 39.53万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/host-metabolism-responses-replication-pathogenesis/518828
• 关键词: Host; metabolism; responses; contributing; flavivirus

We aim to determine how viruses affect the cells they infect, In particular how they can alter the metabolism and balance of lipids in cells and how this impacts the bodies capability to respond immunologically. We believe that by understanding these basic principles we can target ares fr antiviral therapeutic potential.

我们的目标是确定病毒如何影响它们感染的细胞，特别是它们如何改变细胞中脂质的代谢和平衡，以及这如何影响身体的免疫反应能力。我们相信，通过了解这些基本原则，我们可以针对战神病毒治疗的潜力。