ERP & Behavioral Predictors of Language Intervention

描述（由申请人提供）：拟进行两项研究。第一项研究将试图澄清有特殊语言障碍（SLI）的学龄前儿童在多大程度上存在言语处理缺陷。第二项研究旨在确定两种语言干预在特殊语言障碍儿童中的相对优势是否取决于预处理言语处理能力及其行为相关因素。本项目将招募60名处于布朗氏I - IV期的特殊语言障碍儿童。此外，60名符合年龄、性别、种族和社会经济地位的正常发育儿童将被用来回答研究1的问题。在进入研究时，语言和语音处理将被测试。语音处理将通过事件相关电位和行为测量来测量。对于研究二，特殊语言障碍儿童将被随机分配到两个治疗组中的一个：环境语言教学（MLT）或广泛目标重铸（BRT）治疗。这些儿童将接受1:1的治疗，每次30分钟，每周3次，持续6个月。在治疗阶段，治疗后立即和两个后续阶段将再次测试两次语法。表达性和接受性语言和言语处理的一般测量将在最后阶段重复。将采用多元回归、多元置换检验和生长曲线分析对研究问题进行检验。要求提供五年的经费。

DESCRIPTION (provided by applicant): Two studies are proposed. The first study will seek to clarify the extent to which preschoolers with specific language impairment (SLI) have speech processing deficits. The second study seeks to determine whether the relative superiority of two language interventions in children with SLI depends on pretreatment speech processing ability and its behavioral correlates. Sixty children with SLI in Brown's stage I - IV will be recruited in this project. Additionally, 60 typically developing children matched for age, gender, ethnicity, and SES will be used to address the questions for Study 1. At entry into the study, language and speech processing will be tested. Speech processing will be measured with event-related potential and behavioral measures. For study two, the SLI children will be randomly assigned to one of two treatment groups: Milieu Language Teaching (MLT) or Broad-Target Recast (BRT) treatment. These children will receive treatment in a 1:1 format for 30 minutes/session, 3/week for 6 months. Grammar will be tested again twice during the treatment phase, immediately after treatment, and at two follow-up periods. General measures of expressive and receptive language and speech processing will be repeated at the last period. Multiple regression, multivariate permutation tests, and growth curve analyses will be used to test the research questions. Five years of funding are requested.