ERP & Behavioral Predictors of Language Intervention

描述（由申请人提供）：拟定了两项研究。第一项研究将试图澄清特定语言障碍（SLI）的学龄前儿童的语音处理缺陷的程度。第二项研究旨在确定两种语言干预在SLI儿童中的相对优势是否取决于治疗前的语音处理能力及其行为相关因素。本研究将招募60名Brown Ⅰ ~ Ⅳ期SLI患儿.此外，将使用60名年龄、性别、种族和SES匹配的正常发育儿童来解决研究1的问题。在进入研究时，将测试语言和语音处理。言语处理将通过事件相关电位和行为测量进行测量。对于研究二，SLI儿童将被随机分配到两个治疗组之一：环境语言教学（MLT）或广泛目标重铸（BRT）治疗。这些儿童将以1：1的形式接受治疗，每次30分钟，每周3次，持续6个月。在治疗期间、治疗后立即和两个随访期，将再次对语法进行两次测试。最后一节课将重复对表达性和接受性语言以及言语处理的一般测量。多元回归，多元排列测试，和增长曲线分析将被用来测试研究问题。已申请五年资助。

DESCRIPTION (provided by applicant): Two studies are proposed. The first study will seek to clarify the extent to which preschoolers with specific language impairment (SLI) have speech processing deficits. The second study seeks to determine whether the relative superiority of two language interventions in children with SLI depends on pretreatment speech processing ability and its behavioral correlates. Sixty children with SLI in Brown's stage I - IV will be recruited in this project. Additionally, 60 typically developing children matched for age, gender, ethnicity, and SES will be used to address the questions for Study 1. At entry into the study, language and speech processing will be tested. Speech processing will be measured with event-related potential and behavioral measures. For study two, the SLI children will be randomly assigned to one of two treatment groups: Milieu Language Teaching (MLT) or Broad-Target Recast (BRT) treatment. These children will receive treatment in a 1:1 format for 30 minutes/session, 3/week for 6 months. Grammar will be tested again twice during the treatment phase, immediately after treatment, and at two follow-up periods. General measures of expressive and receptive language and speech processing will be repeated at the last period. Multiple regression, multivariate permutation tests, and growth curve analyses will be used to test the research questions. Five years of funding are requested.